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Message
Posted by hisdad on October 28, 2000 at 05:58:39:

In Reply to: Endoscopy and a Colonoscopy: Need advice. posted by Dan on October 27, 2000 at 14:27:04:

Dan and Lynda,

Lynda - thanks fr sharing your story, you are the first person we have heard of that tried this too!!

Dan - do you know that 1) the endoscopy will tell you whether your son has upper gi problems such as esophagitis or acid reflux and 2) the colonoscopy will tell you if he has pollips or other problems in his colon? We did both and found reflux, no pollips. Refer to the abstract below - Horvath is the dr who worked with Victoria Beck to do the early secretin work. Anyway, after finding reflux, we put my 4 year old son at the time on Prilosec, an acid reducer. I've heard anecdotal results with Zantac and Prevacid as well - look this board past messages. We also did gluten and casein peptide blood tests (call Alletess Labs 800-225-5404 in MA to send you a kit), to verify that a gfcf diet would do anything. It did - he was poff the charts. Between the gfcf and the daily prilosec, we have seen truly remarkable results. His diarhea cleared up within just a couple of days, and has not returned after about 10 months now. He had problems with potty training, but after the prilosec, he was potty trained also within a couple of days. It seemed like he knew how to do it, but there was something keeping him from it. It was unbelievable how quickly it happened. He is doing awesome at school, he comes to greet me when I get home from work and says daddys home or hey daddy unsolicited. Good luck with the procedure, it will be hard but worth it. Be there with him until he goes to sleep, and whatever you do be there when he opens his eyes. Don't let the nurses tell you otherwise. Make sure ahead of time that the drs and nurses know he has problems and really be adament that you be there for him when he wakes up.

By the way, gluten/casein free has been great for my son. We work hard to find things he likes. see www.gfcfdiet.com and lisa lewis's book. My son now eats gfcf pizza, ice cream, cream cheese, potato chips, waffles, french toast, cereal, rice milkl, lots of things. If you want more info let me know.

Bruce

Gastrointestinal abnormalities in children with autistic disorder [see
comments]
Horvath K, Papadimitriou JC, Rabsztyn A, Drachenberg C, Tildon JT
J Pediatr 1999 Nov 135:5 559-63

BROWSE

:
J Pediatr . Volume 135 . Issue 5
VIEW

:
MEDLINE, full MEDLINE, related records

Abstract

OBJECTIVES: Our aim was to evaluate the structure and function of the upper
gastrointestinal tract in a group of patients with autism who had
gastrointestinal symptoms. STUDY DESIGN: Thirty-six children (age: 5.7 +/- 2
years, mean +/- SD) with autistic disorder underwent upper gastrointestinal
endoscopy with biopsies, intestinal and pancreatic enzyme analyses, and
bacterial and fungal cultures. The most frequent gastrointestinal complaints
were chronic diarrhea, gaseousness, and abdominal discomfort and distension.
RESULTS: Histologic examination in these 36 children revealed grade I or II
reflux esophagitis in 25 (69.4%), chronic gastritis in 15, and chronic
duodenitis in 24. The number of Paneth's cells in the duodenal crypts was
significantly elevated in autistic children compared with non-autistic
control subjects. Low intestinal carbohydrate digestive enzyme activity was
reported in 21 children (58.3%), although there was no abnormality found in
pancreatic function. Seventy-five percent of the autistic children (27/36)
had an increased pancreatico-biliary fluid output after intravenous secretin
administration. Nineteen of the 21 patients with diarrhea had significantly
higher fluid output than those without diarrhea. CONCLUSIONS: Unrecognized
gastrointestinal disorders, especially reflux esophagitis and disaccharide
malabsorption, may contribute to the behavioral problems of the non-verbal
autistic patients. The observed increase in pancreatico-biliary secretion
after secretin infusion suggests an upregulation of secretin receptors in
the pancreas and liver. Further studies are required to determine the
possible association between the brain and gastrointestinal dysfunctions in
children with autistic disorder.

MeSH

Autistic Disorder (*CO/EP), Child, Preschool, Diarrhea (CO/EP), Digestive
System (ME), Disaccharides (ME), Duodenitis (CO/EP), Duodenum (PA),
Esophagitis, Peptic (CO/EP), Female, Gastrointestinal Diseases (CO/*EP),
Human, Malabsorption Syndromes (CO/EP), Male, Paneth Cells (PA), Prevalence,
Receptors, Gastrointestinal Hormone (ME), Secretin (SE), Support, Non-U.S.
Gov't, Up-Regulation (Physiology)

Author Address

Department of Pediatrics, University of Maryland School of Medicine,
Baltimore, USA.

CAS Registry Number (Substance Name)



: We have an appointment scheduled with a doctor familiar with Autism. I would appreciate any advice from others who have had this done for their child.
: My son is a 4 year old with severe eating issues that have gone from bad to much worse recently.

: Dan



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