As a rule, the drugs that give LARGE changes in BP are:
Diuretics...results can be HUGE in the salt sensitive population
Beta Blockers...some of those suckers can knock your BP socks off and of course this class is rife with horrid side effects
ACE inhibitors...potent but less than the first two.
Very Small benefits:
Angiotensin Receptor Blockers (ARB's)...usuallly in the realm of 10 points systolic, 6 diastolic
Calcium Channel blockers...same small reduction.
ARB's were developed because everybody COUGHED from the ACE inhibitors so these work less well with less hacking.
Calcium Channel blockers were developed to treat heart failure and angina...not hypertension; same for beta-blockers. But since doctors NEVER met a high priced drug they didn't like, they get prescribed for hypertension...and headaches...and rhythm disturbances...and soon, probably for TEETHING problems
The only drugs developed SOLELY to fight hypertension were the thiazides and the ACE inhibitors (Vasotec and her hacking sisters.)