I can't help with the cancer part, but I just had my TT on Feb 28th.
The first 6 hours after surgery were rough for me, I got sick from the anestesia and my neck muscles were sore. By the next morning I was fine. I showered when I got home, was able to sleep really well. I drove on the 3 rd day after surgery. ( I was not taking pain meds)
So the surgery was pretty easy.
Hopefully someone else can fill you in on the RAI part