My daugter is 11 as of yesterday and I am brand new to this site. She was diagnosed with CRMO in May of 2008. She is currently on many drugs. I give her injections of methotrexate and she was just taken off of Remicade. She has tried Naprosyn and just about everything else. She is having her tonsils out in Jan. and then she will try Enbrel with the methotrexate. We live in Ohio and just traveled to Iowa to see a dr. who researches the disease. I look forward to hearing back from you. My daughter is struggling with this disease.