I'm sorry, I can't answer your question. I have visible inflammation around all the joints in my hands, feet, wrists and ankles. Yet, the last time my blood was tested two months ago, my ESR and CRP were in the normal range. I received a new requisition for blood work a couple of days ago. In addition to the usual tests (ENA, ESR and CRP; and anti-CCP which in my case is positive), this requisition includes a few new ones as follows:
- dsDNA (which is specific for lupus)
- Complement C3 and C4 (which apparently rise before ESR and CRP)
The complement system is a group of proteins that work with the immune system. They play a role in the development of inflammation. Perhaps you could ask if it would be appropriate for you to have your blood tested for C3 and C4. This might give you an early confirmation of inflammation.