I am just curious if any one else has had trouble losing weight while being hypo? I had 85% of my thyroid gland removed about 3 years ago. My levels had finally stabilized until just recently. I have increased my dosage of Synthroid from .75 to .88 due to showing hypo once again. My question is how many of you have had trouble losing weight even after stabilizing the thyroid? And also, how have you lost the weight. Seems like the only thing that helps me is low-carbing. Anyone else? Low fat, low calories just seem to do nothing for me, except make me worse. Anyone have any input on this issue? Thanks a bunch! Kim - P.S. Also, how do you keep the motivation long enough to really get going on a good diet, without getting depressed and giving up?