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Old 02-15-2011, 05:34 PM   #5
Isotope Isotope is offline
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Re: Long Term Pain Management??

Tolerance was a real problem for me when I took Vic, and Norco but not so much with Opana......

I'm not sure if there are stats regarding various Narcotics and which, if any, are more prone to tolerance effects? Some find tolerance and loss of effectiveness to be a problem with OxyContin. After a few weeks on Oxy I was ready to double up the dose because the pain just crept back in.....

Generally speaking -steady is what helps keep tolerance down. Finding a dose and sticking to it, keep the blood plasma level from having spikes and dips is what will help.

I'm in the camp that says 'take a low dose of a potent drug, rather than a high dose of a weak one.' Others (J-Star) may have thoughts on this too.


Last edited by Isotope; 02-15-2011 at 08:39 PM.