I have Ulcerative Colitis and to make a long story short I have been suffering with terrible rectal pain for the past two months. Advil is a huge no no for me, tylenol is like nothing, percocet 5mg made bp, heart spike shakes sweat and I totally could not work. I have used tramadol a couple of times because I have to find something to control pain where i can work without getting all loopy. Well it has a very strange effect, starts off by putting me in a strange good mood, does work for pain, but i feel jittery like I am coked up. After several hours, since I can't go to sleep b/c I am at work, I get nauseous, weak and sometimes pain in my left arm. I took it last night and I still feel jittery, had a hard time sleeping because the brain won't shut down and my insides get so jumpy. Will these effects go away, I am desperate because I have to find something for the pain so I can keep working.