Hypogammaglobulinemia & CVID
I am so confused. I am awaiting the results of all blood work from second lab. I am a 56 year old male with a history of sinus infections (& allergies). My ENT dr did not want to speak for allergist/immunologist, but he suspects sinus infections are related to low antibodies and she "might" want to boost my immune system.
First lab noted "Hypogammaglobulinemia is present". One month later (3/17) I was retested along with additional tests. While some lab results have been released, Dr says waiting for additional results for interpretation. So far what I have is:
Component Standard Range 2/17/2012 3/17/2012 Change
IGG QUANT 751-1560 MG/DL 637 622 -15
IGM QUANT 46-304 MG/DL 27 24 - 3
My IGA & CBC are normal. As you can see, my IGG & IGM dropped slightly since last month. I was under the assumption that, if they could not find a cause (cancer, etc.) it must be CVID.
I was just told by a source (not my Dr) that my readings are mild & not significant. This same source told me that for CVID the IGA MUST be below normal. So this all sounds like good news in my case.
But that leaves me confused about Hypogammaglobulinemia, CVID & lab results. Does Hypogammaglobulinemia get worse, or is it stationary (you have what you have)? And if no cause is found and don't have CVID, does that mean I'm just a little prone to infections? Why would labs scores be different and what is clinically significant?
If anyone could provide insight, it would be appreciated. I just want to understand.