Re: Extreme weakness left leg
I would explore more neuro tests, and skip the muscle biopsy for now. A recent MRI of brain and spinal cord should be done. You are at age where even a herniated disc could be causing the problem, but that normally involves pain. If the problem is in the muscle you should have elevated CK enzymes on blood. Have those been tested? Did they do a nerve conduction test along with the EMG? The EMG sounds like it was normal so I think a muscle biopsy will be normal unless CK is elevated. There are uncommon things, like arterio-venous malformations in the spinal area that can wrap around the nerve and kind of strangle it. Is there pain in that leg or your back or buttock? Reflexes normal? From what you've said thus far, it sounds more neurological than muscular. You might consider going to the Scripps Clinic in La Joya Calif if you can't get answers where you are.