Re: Renal cortical thinning and increased renal mudullary echogenicity.
I would agree with your Dr that this sounds like an autoimmune disorder. Unfortunately, sometimes the symptoms of AI diseases start before the laboratory confirmation tests become positive. I would recommend that you get a new test called AVISE SLE that is more sensitive that the standard ANA. Your rheum office may have the kit, or the Drs office or you can request a kit be sent to you free of charge, which you then take to the Dr's office and lab. Lab will need an order from your Dr to run test. You can find the specifics for it online. I would also see a nephrologist for evaluation of what is going on with the kidneys, as that can be a part of autoimmune disease as well. ALL of your symptoms could be explained by an AI disorder. About 5% of people with lupus have negative ANA's, and many more get symptoms prior to ANA showing up positive. Many Drs will also treat patients based on a presumptive diagnosis so you can feel better and function better. I would discuss that with your rheum., and hopefully she will agree, since you have so many symptoms that are suggestive. Please keep us posted. Good luck and take care.