Hello! I have IC and I have tried the Elmiron and I had terrible side affects. Severe headaches, I couldn't focus on anything. I have to stay on a real strict diet, anti-inflammatory. No accidity foods or drinks. Orange juice or cranberry juice is a no no for me. I also have problems with kidney stones and fibromyalgia. They have a product called prelief, it works while you eat, neutralizing acid in food.