| Re: why not drugs for tightening instead of PPI's?
Simple: they don't exist.
Well, some pro-kinetics are thought to maybe help tighten (but not definitive). Reglan is an example but lots of people apparently have severe psychotic episodes with it.
Essentially, the technology just doesn't exist. It's true that, even now, medical science doesn't have the answer to everything.
My hope is that in my lifetime, researchers will come up with a way to tighten it WELL, either medicine or surgically (fundo is unreliable and often leads to other problems).
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