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Old 01-26-2008, 01:46 PM   #1
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chormie HB User
Nodule in the esopgagus

Hi....I just had an EGD in which three nodules were biopsied from the esophagus, and one from the stomach. In addiition, they found evidence of reflux esophagitis and the mucosa was edematous, erosive and erythematous.....what does that mean exactly? Protonix was prescribed and I need to re-visit my doctor in three weeks. There is a strong history of cancer in my family. What is the likelyhood that the results will reflect any type of cancer? And, if they are not dangerous in that sense, will this medication simply stop the discomfort, or will it help actually correct the problem?

Thanks for any insight you can provide.

 
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Old 01-26-2008, 02:53 PM   #2
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HasLPRD HB User
Re: Nodule in the esopgagus

Reflux is almost always due to dysfunction of the lower-esophageal
sphincter (LES). While many different things can exploit that
weakness to cause reflux, an LES that is incompetent in some
way is almost always a factor. Did they say anything about your
LES... find a hiatal hernia or whatnot? Did they say anything
about Barrett's esophagus, which is a pre-cancerous condition?

Erosive means the mucosa has been damaged. It's beyond irritation
but short of ulceration. Edematous and erythematous just means it's
swollen and red.

The medication will merely suppress stomach acid production so
that the erosion, edema and erythema can heal. It will not
address the reason why stomach acid was bubbling up into your
esophagus. Have you had reflux symptoms (heartburn, etc...) for
a long time? Have you been taking care to avoid it with the
standard diet and lifestyle changes?

As for the nodules, I couldn't say as I don't have any statistics.
I believe, however, that most people with reflux-induced esophageal
cancer have had Barrett's esophagus first.

Mark.

 
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