High concentration of eosinophils in just part of esophagus? Eosinophilic esophagitis
My husband has been having constant, severe esophageal pain and stomach distension for the past several months. The local GI specialist diagnosed him with Barrett's Esophagus (based on EGD) and tentatively diagnosed him with eosinophilic esophagitis. However, they have been unable to find any treatment that is effective at all. PPIs (including Nexium) have no effect, and neither has the swallowed steroid.
We got a copy of his medical records, which provide much more detail than the doctor explained to us. Most interesting to me, the EGD results said that he had a concentration of 30-35 eosinophils in ONE high power field in the esophagus, but that there was only a "sprinkling" of eosinophils in the rest of the esophagus.
What could it mean that the eosinophils were highly concentrated in just one part of the esophagus? I have been wondering if he has a bacterial/parasitic infection because the only thing that has provided any relief is Xifaxan (which attacks bacteria and parasites), but he was only allowed to use that for a few days. Could the high concentration suggest something in particular?
Any thoughts appreciated. Thanks.