Well, as for the drinking, I am on my 2nd month, and last month I drank on the weekends and got pretty drunk I must say, and my tests came back fine. My doctor never said anything about not being able to smoke, so I think that's fine as well. About the basketball, as long as you can handle it, than play all you want. Sometimes my joints get a little stiff from the accutane, but if that happens to you, i'm sure you'll know to sit out for a little while. For me it's not really painful, but you can feel it stiffening up. Hope that helped!