Originally Posted by cherilyn
Hi Joeh, I have seen alot of your comments on spiro and thought I would write to get some advice. I have been on spiro for a year and 3 months. I had to go off it for about a month due to some irregular blood readings (this was about 3 months ago) . I have since continued on the spiro because readings came back fine but at a lower does (50 mg). well the past 2 months, I have been getting the cysts back (always around my period and on my chin) and I'm scared now that the spiro isn't working anymore. So i have recently gone back up to 100mg to see if that will help. My questions is... how much do you take and do you think that 50 mg is not enough. Also, how long will you stay on it. Did your doctor have concerns with you taking it for long periods of time?? I'm just worried that my body has become immune to it. Any comments would be appreciated
First off I'm obviously not Joeh, however I may be able to help a little. As far as I know Joeh takes roughly 100mg a day of spiro, and another product called premarin if I'm not mistaken. As far as the question regarding the continued efficiacy of spiro, you need to remember that spiro works at two sites: it competes with androgens at the hair follicle (receptor site) and oil gland (receptor site) and it diminishes the production of male hormone at the adrenal gland. According to Sweetjade (I think she said something to this effect), theoretically spiro's effects could be diminished because your hormone receptor sites could shut down only to reopen elsewhere.