I take Zoloft, and while it has been a lifesaver for helping prevent migraines and depression, it is definitely not a cure for acne by any means. In fact, I don't think it affects it one way or the other, and is totally unrelated. However, if your skin problems are due to stress or depression, then it might help. I just wanted to point out that Zoloft is not designed to treat acne.
[This message has been edited by poreoilyme (edited 06-04-2003).]