i'm taking chromemate gtf chromium. i can't really say if it's helped at all. it's been about three weeks i think taking 200-400mcg a day. i'd stay away from chromium picolinate b/c there is evidence of mutagenic effects on dna chains. there's no evidence that this has had any effect on humans or that it is carcinogenic taken within the upper limit guidelines, but best to err on the side of caution, imo.