Hi I am still vey new to stimulants and this forum. I have been on addderall ir for about 5 weeks now for add. I also take subutex(16mg ed) for opiate dependence) and klonopin 2 mg at bed time for sleep issues. I was recently upper in my adderall dose to 20mg ir 2x a day for a total of 40mg a day. Needless to say tolerance has become an issue as the medicine is not having a positive effect any longer. I know that I'm not supposed to feel high or anything but I no longer get the increase focus and alertness that I need and why it was prescribed. I'm getting all the negative sides like sexual and decreased appetite. I can deal with the food thing ok but the no sex thing is a killer. I tought opiates were bad for sex but adderall is way worse! Well I told my doctor and he told me to take days off and that will lower my tolerance. Also I decided that I wasn't needing to take it everyday and should only take it when I need it. Does anyone else do this and how effective is it? I've done a lot of research and it sounds like my best option here as I can't keep upping my dose. Also my doc feels that the subutex(which makes me very groggy and tired all the time) is having a effect on the adderall and the way I respond to it. That was the other reason I was put on adderall, because the subutex was making me fall asleep all the time! I was falling asleep while driving constantly and could not control it and that was getting extremely dangerous. I have not decided exactly how I'm going to dose the adderall or what days on or off or low doses on some and my prescribed dose on another. That's where I'm at now.. I'm lowering my dose so I can come off for a couple days and try and find a method that works right. But its so hard to figure it all out. This drug and the tolerance with it is sooo different than anything I have ever seen. I need to find a balance where I only take it on days I really need it. Or a small dose if I'm tired and have to drive. Someone must know more about this and can give me some advice please. Thanks
Amphetamine tolerance is tricky, as it's very specific to the individual, we all develop tolerance at different rates, while some even become sensitized.
To my knowledge, there is no hard and fast system for avoiding tolerance, though taking days off is often given as an option. I, myself, have found that taking my Adderall consistently offers me more effect than missing days.
Are you on the Adderall only because of the Subutex? If so, then I would definitely treat the Adderall like caffeine and use it only when required. Unfortunately, many factors can affect the overall effect of Adderall, including sufficient sleep, and other drugs, like Klonopin and Subutex, that cause opposite effects.
Also, are you certain that the loss of libido is the fault of the Adderall? Decreased libido is a listed side effect of both Subutex and Klonopin, but would be considered a paradoxical effect for Adderall.
No I have add also. So it was being used to treat both the falling alseep all the time and trouble completing things, focusing and all that fun stuff. But its not gonna do me any good the way it was working taking it daily. I feel like taking only when I feel its really needed will keep my tolerance low enough so that it will have the positive effect it had initially. Maybe I won't need a full 40mg on some days and others maybe I will. I guess I'm gonna have to just go with the flow and see if it works out. As far as the sexual side yea I'm sure its from the adderall. I have been other the other 2 meds for years and have been fine. The day I started on adderall I have not gotten let's just say excited since(even in the morning) its like completely out of service! Lol not good. Its looks like the life was drained out of the whole area down there. It went back to normal when my script was stolen a couple weeks ago and I went off for 5 days. I thought opiate treatment was tricky. This stuff is way more complex! I would never ever consider not taking my subutex everysingle day. I have been on that for over 5 years and I still get a buzz off my maintenance dose. Its just crazy
Just a quick update. I did take a day off yesterday and also bought magnesium and l-tyrosine to help out. I plan on taking the magnesium on days I use adderall and the tyrosine on off days as it seems to help with the fatigue and puts me in a better mood. I did end up taking 20mg today a little while ago because it being friday and I work maintenance at a mall so its very busy and hectic. It did seem to have a bit more positive effect even from just one day off. I don't know if the magnesium helped at all but it can't hurt I guess. I don't plan on taking a second dose today and later if I feel rum down ill take some l-tyrosine and maybe a cup of coffee to help out. Tomorrow will be an off day as sunday I have a lot of driving to do and a long day so I am planning to take 20mg before I leave on the trip and maybe a second dose later if need be. After that I plan on taking atleast 3 or 4 days off just to get my tolerance down low and like thunor said take it like caffeine as needed. The subutex definitely has a counter effect on the adderall so I might need to change to the 30mg ir pills down the line because I'm a pretty big guy and it will give me a larger initial dose and less pill breaking and I have found 30mg taken at once to be my most effective dose. Maybe something like viagra will help on days I take addy if I need to function sexually? My doc would be open to that(prob even give me his free samples) I also got a greta nights sleep last night after my day off. I went to sleep at 1am instead of 3am and needed only 1mg of klonopin to sleep through the night. Usually I need to take 2mg at least 2 hours before I want to fall asleep on days I was taking adderall 2x daily. I think that 2nd dose was really doing it. I also find when taken everyday the 2nd dose was just making the negative side effects worse. So over all I feel much better today and plan on taking it as need. It is getting easier to not take it everyday as I see the better results coming from this usage schedule. If anyone else would like to give any additional advise or opinions please do... I would like to get as much info and input from more experienced adderall users as possible to help in my adjustments and usage of this medication. Thanks again. Mikey