Re: Mood change when Adderall wears off
I used to have a similar issue with irritability. Tolerance with amphetamines goes up rather quickly. So, in a way you are dealing with withdrawals.
If you don't like upping your dose, I would start taking weekends off. Try to loose some of your tolerance to the drug. It could actually take, from what I understand" weeks or more to get back to the tolerance you had a year ago.
As for irritability. I found that a Cal-Mag solution worked wonders form me.