I just mentioned that I used that in detox myself.
Probably the most important thing to watch is your blood pressure since that's it's main use. In detox, obviously they monitored that periodically - limits were to give it if above 100/60. One night I almost passed out standing, lost my vision for a few secs, then when they took my BP, it was 80/50, whoopsie! So the dose was lowered.
Did it help? Hard to say, since it's not like you get a "feeling" like from taking a narc or something... but since the detox wasn't too awful for me, it must have been doing something?
I sure wish I had something now though. I feel like I'm about to jump out of my skin!
Good luck m'dear,
~pb