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Old 06-04-2006, 03:05 PM   #1
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Anyone tried Lyrica? Wondering about the addiction potential?

Hello all, i have chronic back/nerve pain in my legs due to a SCI from a burst fracture. You could call me a walking SCI. I have taken neurontin and i don't like it, i am also withdrawing from ultram (24 days now!) I think i need something for the nerve pain and the doctor mentioned lyrica and so i googled it and found out it is controlled? but i haven't seen any reports here about anyone getting hooked on it. Just wondering if it is addicting, addiction sucks (and i also think dependancy sucks, just me) anyone?

Thanks!

 
Old 06-05-2006, 04:05 AM   #2
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Re: Anyone tried Lyrica? Wondering about the addiction potential?

anything that is Rxed is considered a 'contolled substance as it IS controlled in its dispesing merely as it requires an Rx to actually obtain it.so that in itself,really means nothing.

the type of med that lyrica is,is an anti siezure med like the neurontin you were on.it has the same mode of action but has a different med make up,just like totamax or gabitril they all do the same thing but do it by using different base meds.I too suffer from very severe pain both neuropathic and structural/mechanical from a direct spinal cord injury and a couple of other medical problems thrown in just because.i am in the process right now of doing my taper off of the gabitril and will be starting the lyrica myself,by thursday,according to my current taper schedule.

If you scroll on down to the pain boards there are quite a few different threads going there right now just on lyrica alone.I think you would find these very helpful.glad to see you are off the ultram.really good idea there as this med can cause all kinds of various problems as i am sure you have found out the hard way?

I have done alot of research on Lyrica and really do have some hope that it may actually help with my central pain and RSD pain syndromes whcih resulted from my spinal cord injuries.you just have to keep trying the various anti siezure options out there til you find the right one for you.i had some really good luck with the gabitril but it just made me sooo fatigued that I just could not tolerate it during the day at all,i was a walking zombie,even after actually being on it for over two years.that particular side effect just never went away.sooo onto the lyrica.

unfortunetly neuropathic pain is one of the very hardest to try and control as you are not actually treating a real source of a pain(like with an actual injured area?) but the ingrained memory of it ,or some mutated crap that came from just the nerve damage itself.i do wish you luck with the lyrica,i am hoping that it can offer me some little bit of relief from the horrid ongoing agony in my leg and my arm over my shoulder blades.good luck,and let me know how it goes for you.Marcia
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3-22-01,herniated C-6-7
11-20-01,placement of hardware for failed fusion
9-22-03,removal of cavernous hemangioma that was inside spinal cord. Neuro damage to L hand L leg and R leg.

 
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Old 06-05-2006, 10:09 AM   #3
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Re: Anyone tried Lyrica? Wondering about the addiction potential?

Actually, I think Feelbad may have misunderstood the control issue with meds. The level of control is actually related to it's addiction potential as you guessed it is. There are 4 "schedules" of control. Sch 1 is highly addictive with little or no therapeutic value, like cocaine or heroine. Sch 2 is pure opiods(no tylenol mixed in) or highly addicting opiods, like codeine(alone) or percocet. Sch 3 is your hydro's, T'#3's, opoids mixed w/limiting agents(the tylenol is "supposed" to lesson our abuse of it, haa ha, we all know that only goes so far!) and sch 4 is less addicting things like ambien, stadol, some cough syrups. It's called controlled b/c the DEA controls their dispensing by keeping counts of who prescribes/dispenses it. Pharmacies and hospitals must count their stock at change of shift b/c if abuse potential.
So if Lyrica is controlled then it's got abuse potential. I don't know enough about it but I did read an ad and on the back it said it should not be given to people with a history of drug or alcohol abuse. I think that sums it up right there. I'm still gonna look into it though myself b/c I know that it's not true for everyone but I only have problems with my DOC, and can take others without abusing them, I don't know if that's the norm though. Good luck to you, if you do get relief from your nerve pain, pls let us know. Take care,
Leora

 
Old 06-06-2006, 06:49 AM   #4
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Re: Anyone tried Lyrica? Wondering about the addiction potential?

there are actually 5 schedules and lyrica is listed as a schedule five non narcotic.i just looked on the DEA web site.the difference between the schedules and being a controlled substance are really ather confusing at best.from what i was reading,there appears to be some part of a particular 'drug" that has a potential more for harm than addiction/abuse.or part of the actual "chemical chain" that this particular med is made up of,wayy back at the beginning of that chemical chain,there was once some sort of a med that was related to some sort of a drug that had some kind of abuse/harm potential??they just don't really explain it all that well.

they actually have the list of controlled substances on this website that also include their schedule numbers as well,they include the narcotics and barbs and also things like anabolic steriods.it appears that what the controlled substances all have in common is that some part of them can cause harm in some way??i am not really sure.but it definitely does list lyrica as a schedule five with no actual abuse potential(thats what schedule five actually means),so I will have to actually look into this a bit deeper and see just whay lyrica is actually considered as a controlled substance while none of the other anti siezure meds are when they all basically work in the same way.

it does appear that certain derivatives,and things like salts,isomers,esters also play some part in this too.geez.like things arent bad enough.maybe i will just ask my pharmacist.

but the actual 'schedules" are what DO indicate the abuse potential and controlled substance is a totally different thing.i would just like to know for myself,what that is since I am starting this med on thursday once I taper off my gabitril.

when I looked up controlled substance in the online law dictionary all it states there is that it is basically 'any drug that has been declared by either federal or state law to be illegal for sale or use in the US but may be dispensed under physicians Rx.well geez,we know THATS not exactly true either since all illegal drugs are also controlled substances as well,even the schedule "I"s,like LSD.go figure.like I said its all a bit confusing.I just want to know what kind of anti siezure med I am taking.marcia
__________________
3-22-01,herniated C-6-7
11-20-01,placement of hardware for failed fusion
9-22-03,removal of cavernous hemangioma that was inside spinal cord. Neuro damage to L hand L leg and R leg.

 
Old 06-12-2006, 06:41 AM   #5
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Re: Anyone tried Lyrica? Wondering about the addiction potential?

Well,after going directly to the pfizer(the drug manufacturer)web site and reading thru alll of the fun and exiting in depth Rxing info on this med,I think I DID find the answer to the question.

bear with me here while I try and do a readers digest version on what i found,K?well it appears that when they were doing the drug trials on lyrica and keep in mind(and I don't know why in the heck all drugs are actually teated this way)that all of the drug trials were done using levels of the drug that were much much higher than what the normal Rxing dose would be for a given patient.they actually tested using 450mgs per dose at a time while the actual Rxing info states,for use in pain and not siezure control,only 100mgs per dose at a time and with the max amount for pain patients being around only 300mgs per day.

well,during the trials,if you are not really familiar in just how the info gets into the Rxing literature,when ever any of the test subjects report ANY possible symptom or adverse reaction,it HAS to be listed,but it goes on a scale from most frequent complaints to frequent to rare in nature.so if even one person stated something,its in the lit.soo it does appear that while testing in 5500 patients,that this recieved subjective ratings from some subjects as it giving feelings of (and some of the test subjests were recrecational drug users??go figure)"a good drug effect",'high' and 'liking to a degree of that was similar to diazipam(30mgs of).in the 5500 patients there was 4% who were actually given the lyrica and 1% of placebo treated pts who overall reported euphoria as an adverse event.

also in clinical studies ,following abrupt or rapid discontinuation of lyrica some pts reported symptoms of insomnia,nausea,headache or diarrhea,which is suggestive of physical dependancy(which can actually happen with any med that you are taking on a long term basis that needs tapering up and off like all of the other anti siezure meds so I dont understand this actually being an issue in itself?)

now it also states that lyrica is NOT known activate receptor sites associated with drugs of abuse,but as with any CNS acting med, physicians should carefully evaluate patients for history of drug abuse and observe them for any signs of possible lyrica abuse or misuse,such as development of tolerance(which happens with alot of different types of meds)dose escalation and any drug seeking behavior.

the max dose for pain patients should be 100mgs three times per day,doses above 300mgs a day is not reccomended.

sooo condidering that these tests were all done at an amazing dose of an actual 450mgs PER DOSE at a time,i do think some of these reported symptoms would not actually even be an issue here really,and the fact that even despite the the very "rare" occurance of what was reported as euphoria and the"good drug effect" and the "high',in very few pts in this study at a very high dosage at the time and the fact that the FDA is still sticking with the schedule 5 and not even going up to even a 4 with that info that was reported,i do think any real abuse potential is practically almost non existant or the FDA would have not let this 5 even be there.it would have most definitely demanded a change.

so I do belibve that the reason for the 'controlled' label is merely because of what happened during the drug trials with those few rare comments so they had to place that on this particular drug.

I have no probelm in actually taking this med at all.and actually am on day four of it with some actual reduction in the,what was before non stop constant swelling in my RSD knee,nothing had even touched that before,I am rather amazed with that already.we will just have to see how it goes.

but thats it in a nutshell.you can find the same info,in a very long version,just by going to pfizers website.at least we do have an explanation now so I thught i would let you guys know.hope it helps.Marcia

Last edited by feelbad; 06-12-2006 at 06:41 AM.

 
Old 06-12-2006, 11:44 AM   #6
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Re: Anyone tried Lyrica? Wondering about the addiction potential?

I've taken Lyrica on and off, two previous occasions. It's a much "cleaner" drug than neurotin and I haven't noticed any sort of high, even when going on a fast taper; I have noticed a type of calming effect, maybe this is why it's good at treating my nerve related pain. This distinct effect is not felt after I've been on maximum dose for over 2-3 days. Addicts will try and aduse anything that has an effect of sorts, I guess that's why Lyrica has been scheduled level 5 (amongst the other reasons that you've all quoted, of course.)

 
Old 06-12-2006, 05:11 PM   #7
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Re: Anyone tried Lyrica? Wondering about the addiction potential?

Very good info, thanks for looking that up. I just hope they don't find out later that it's addicting or habit forming. At one point in time when Ultram first came out, I believe they said it was non-addicting since it wasn't a true opiod. But we all know that's not the case. It would be nice if we did have a nice pain reliever that was non addicting for a change.
Take care
Leora

 
Old 06-13-2006, 07:04 AM   #8
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Re: Anyone tried Lyrica? Wondering about the addiction potential?

hey blaster,that calming effect could be what they were referring to where it stated in the literature that what those few test patients related lyrica to was diazapam(valium?)which most people here know is indeed a tranquilizer.makes sense.but the test subjects were also getting much much higher doses than the reccomended dose really is(if i remeber what i posted before,it was actually like around 450mgs,compared to the 100mg reccomended dose at one time).It appears from what i have read in the past about meds and drug trials,for some bizarre reason,they all seem to actually test the meds at much higher doses than any normal patient realistically would.it just seems kind of stupid and not actually realistic to what you would normally be taking,ya know?

leora,I know what you mean about the new meds that come out and the claims they make about safety and what a wonderful med it is only to find out down the road when some awful things start happening to the people on these meds that they appeared to have somehow 'missed' something during the trials??the FDA really needs to be able to have much more time before the actually okay any med before they give it that stamp of approval and the docs start writing all of those Rxes.

unfortunetly,it all comes down to money and the drug companies wanting to push their newest wondermed so they can start raking in those big bucks.very sad.we are all just guinea pigs for the big drug companies so they can 'continue' that drug trial.

I have been on the lyrica for about five days now and am having some good results and of course,some side effects too,but not half as bad as when I tried cymbalta last year,now THAT was a flippin nightmare.I was just totally "sick" with that stuff.

If I hear anything new,i will keep ya posted.Marcia
__________________
3-22-01,herniated C-6-7
11-20-01,placement of hardware for failed fusion
9-22-03,removal of cavernous hemangioma that was inside spinal cord. Neuro damage to L hand L leg and R leg.

 
Old 06-13-2006, 11:38 AM   #9
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Re: Anyone tried Lyrica? Wondering about the addiction potential?

Feelbad, just curious, what is "cymbalta" and what was your experience with it. I've never heard of it, is it for nerve pain too? Thanks again for all your info and for taking the time to post it. Take care
Leora

 
Old 06-14-2006, 06:30 AM   #10
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Re: Anyone tried Lyrica? Wondering about the addiction potential?

yea it came out last year with alot of the same wonderful claims as the lyrica now has.some people really have had great success with it but unfortunetly it caused me some major side effects.but everyone is very different when it comes to just how they will respond to any med.its up to your basic body chemistry along with any other meds you may be taking and a bunch of other things that all play a part in any given med response in any individual.it could work for you.

it is clamed to be an anti depressant along with the benefit of helping control neuropathic pain.

you may want to actually look into this as a possibility for your pain.just a thought.dealing with neuro pain is just a constant game of trial and error til you find that right combo of meds that will give you at least some relief from the ongoing torture of this particular type of pain.

i am kind of suprised you haven't actually seen any of the hundreds of commercials they have on tv like every hour on the hour about cymbalta.it seems this commercial comes on like all the time now.just do some research on it and see what you think.there are some people on the pain board who are currently taking it,you could post a question about anyone who is curently using it to give you any info they have on it from their particular experiences down there?just a thought.

I think I have tried just about everything and anything to try and just get this nightmare inside of my body down to the point where I don't feel like running(or hobbling in my case,lol)down the street to the freeway overpass and giving it a go over the top ya know?god this crap just sucks!good luck in finding something for your pain.luckily we still have some untapped options availiable out there.marcia

 
Old 10-02-2006, 12:00 PM   #11
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Re: Anyone tried Lyrica? Wondering about the addiction potential?

I've been a chronic pain patient for 12 years. For most of that time my pain was managed by Klonopin (clonazepam) and several other drugs. Klonopin did a pretty good job, but I developed a tolerance to it. My pain management doctor ordered me to taper off of it, but didn't provide me with enough Klonopin to do it safely. I suffered a withdrawal seizure and developed Benzodiazepine Withdrawal Syndrome. Now I am dealing with not only chronic pain, unmedicated, but the debilitating symptoms of BWS.

Recently I was taking 2400 mg of Neurontin (gabapentin) daily, but I didn't really know if it was providing me any benefit or not. My neurologist was concerned about the high dosage, so he had me taper down to 900 mg daily. I got much worse, so apparently the Neurontin was doing more than I realized.

I reported this to my neurologist and asked if Lyrica (pregabalin) might not be a better alternative. My reasoning was that Lyrica, which is from the same family as Neurontin, is far more bioavailable, so more benefit can be achieved with substantially less milligrams per dose. He immediately nixed this idea, informing me that Lyrica was a Class 2 controlled substance and not appropriate for me due to my history with Klonopin. (Yes, I read above where it says Lyrica is a Class 5, not a Class 2.)

So I got online and read what I could find about the addictive potential of Lyrica. What I found out was this: Because Neurontin's FDA approval wasn't for pain control, it wasn't subject to the same scrutiny that Lyrica received. In all liklihood, Lyrica is no more (or no less) addictive than Neurontin.

Should I continue to try to make a case for Lyrica to my doctor? Should I be worried about the Neurontin? Any feedback would be appreciated.

Additional note: I can't tolerate Gabitril (tiagabine), a drug from the same family as Lyrica and Neurontin.

 
Old 11-18-2006, 04:00 PM   #12
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Re: Anyone tried Lyrica? Wondering about the addiction potential?

I know someone who was prescribed lyrica for anxiety disorder, and who took the maximum amount mentioned on the lyrica site - 2400 mg. a day - for about 3 months.
That person has become very severely addicted and is having a terrible time withdrawing from the medicine. It is a very severe drug addiction.

No one should take this drug who has a potential for drug addiction.

 
Old 11-19-2006, 03:48 AM   #13
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Re: Anyone tried Lyrica? Wondering about the addiction potential?

hend you must be talking about Neurotin as it's typical dose is 2400mg. Lyrica's absolute max dose that I've heard of is 600mg a day! Having tried both (not on either now) I would say Lyrica had the best anti anxiety potential for me at a low dose; at a high dose I was too sleep to care about much in the way of ailments, lol....

Also I've read that mixing OXY and Lyrica will case excessive sleepiness, this is a new finding.

 
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