Re: Increase Cortef for PMS?
Christy, I would be extremely cautious about increasing since your goal is to someday be free of steroid meds completely, however, estrogen will make hydrocortisone, in your case Cortef, last longer in the body due to the fact that is has CBG, cortisol binding globulin, in it. With the cyclical decrease in your estrogen, your cortisol is not lasting as long at that time. Therefore, an increase is justified. I hope you feel better. And I hope you get off the Cortef someday. Good luck.