I come with yet another request for help analyzing my symptoms and test results. I'm seeing a great doctor who so far seems to be very dedicated, who I'll be seeing again on April 8th, after the last two test results (ADH serum levels and adrenocorticotrophic) arrive.
My doctor's hypothesis is adrenal insufficiency, but the latest test results seem to disagree with that, so I'd like to hear some opinions. I'm aware this is a pacient-to-pacient forum, but any help will be welcome. I'm tired of feeling so bad so frequently, missing class, watching my life pass by while I'm bedridden with overwhelming fatigue.
The symptoms started around September/2010. I haven't been sleeping well since then - on the average, I wake up every 2:30hrs to urinate. It doesn't matter how much I drink or don't. The fatigue got worse this year. Sometimes, out of nowhere it's like my "power cable" is unplugged. I feel completely exhausted, drained, even my speech becomes slurred. My heart rate dropped from around 75-80bpm to 59-60bpm. I get dizzy when I stand up - sometimes only a few times per day, sometimes every single time I sit and then stand. I've been having bloating, flatulence and lose stool constantly. My hair started to fall, nothing excessive but SO much more than it did before.
Lately I've been having salt cravings (and less frequently sugar cravings), and have no appetite even when completely hungry - the thought of food disgusts me.
The stream of lab tests started after in February I got a sudden, piercing pain at my stomach. It was so terrible I couldn't walk. It was like I was being stabbed, right under the lower left side of where the stomach is (I think). I went to the ER and came back home with no answers. There was much noise going on in my bowels, and a sonography just showed there was some fluid accumulated between my intestines. The pain started to get better after three or four days.
When the sudden, extreme fatigue starts, I get very emotional. It could be just me being scared, of course. I've been on treatment for depression before, but stopped the meds (gradually) after two years since other coping mechanisms (better life, physical activity, etcetera) showed to be far more efficient (the meds made no difference, only gave me side effects). Recently I've been very moody, though. Going from crying nonstop (even though I don't really feel THAT sad) to being terribly aggressive.
My most recent lab tests are as follows. Bear in mind I take contraceptive pills, so that's probably why some are a little bit messed up. Also, forgive any spelling problem, English isn't my first language.
TSH: 2.4 uUI/mÁ (range: 0.4 - 4)
FT4: 0.90 ng/dl (0.89 - 1.73)
Cortisol: 34.5 ug/dl (5 - 25)
Prolactin: 18.3 ng/ml (1.9 - 25)
LH: 0.1 mUI/ml (??)
FSH: 0.10 mUI/ml (??)
Serum sodium: 142.0 mmol/l (136 - 145)
Serum potassium: 4.4 mEq/l (3.5 - 5.2)
Serum osmolarity: 294.27 mOsm/K (note it's osmolaRity) (285 - 310)
These were made a few days before:
Direct coombs: negative
Platelets: 226 000 /uL (150 000 - 400 000)
Reticulocytes: corrected: 1.1%, not corrected: 0.9%
VCM: 107.2 fl (my doctor gave me B12 shots since macrocytosis was going on for months even though the B12 levels were around 350, as seen in other tests. I won't be writing the rest of the hemogram results here, as I think it's not relevant. Let me know if it is though!)
Urine pH: 8.0
Urine density: 1 010
Negative for protein, glycose, hemoglobin on urine.
Serum albumin: 3.6 g/dL (3.5 - 5)
Serum bilirubin: direct 0.4 mg/dL, total 0.6 and indirect 0.2
Serum calcium: 9.3 mg/dL (8.4 - 10.2)
24hrs urine chlorides: 284 mEq/24hrs
24hrs urine volume: 4500 mL (and I drank much less than I usually do)
Urine creatinine: 851 mg/24hrs (800 - 2800)
Serum glycose: 77mg/dL (74 - 106)
Serum potassium: 4.4 mEq/L (3.5 - 5.1)
LDH: 444 U/L (313 - 618)
Serum magnesium: 2.2 mg/dL (1.6 - 2.3)
Serum sodium: 142 mEq/L (137 - 145)
Urine sodium: 306 mEq/24hrs (40 - 220)
Serum osmolarity: 287 mOsm/L (275 - 305)
Urine osmolarity: 587 mOsm/L (???)
Urine protein: 405 mg/24hrs (42 - 225)
AST: 18 U/L (14 - 36)
ALT: 62 U/L (9 - 52)
Stool sample showed nothing wrong (no fat, blood, parasites).
Thank you so much for taking your time to read so much whinning and please please please, if you have anything to share, any hypothesis or results interpretation, please do!