Yes, there is hope. I get 5 shots a month (just got them today) and will do so for life. In early 2001, I started once a week--then increased to every 2 weeks and now get 5 every 4 weeks. It took me a few years to get to the every 4 weeks, but can't really go beyond that--
or I get migraines and infections.
I forget when I was able to go off of daily zyrtec, but I did, maybe after 2-3 years of shots. I take one now as needed or when pollens and mold are high or if I have been exposed to dust or animals.
I have always had a hard time taking allergy medicines and nasal sprays, so that was not part of my daily medicine intake.
I would cleanse the sinuses a lot, as that could help get you off of medications. Plus, just giving your body time to rebuild immunity from the shots will help and hopefully get your medicines reduced.