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robine27 02-15-2009 05:15 AM

ferritin low, iron and B12 high, other labs off
 
My hematologist ordered the following bloodwork:

FE(Iron) 155 high, (range 35-150) one month later 101
UIBC 48 low, (range 126-382)
Calculated TIBC 202 low, (range 250-450)
Transferrin Sat 77 high (range 15-60)
B12 1200 high (range 208-964) Has been at this number for 5 years
Several docs were asked about this one and are not concerned.
Ferritin 28 (range 5-204)
Hematocrit 41 (range 36-46)
Hemoglobin 13.7 (range 12.0-16.0)
Platelets 128 low (range 159-400)
RBC 4.25 (range 4.20-5.40) Were low now normal

I had the gene test for hemochromatosis and I have one gene-doc said you need two genes to have the disease. I am having an MRI of the liver to be sure there are no iron deposits in my liver and repeat blood tests next week. I do not take any iron supplements. I eat meat only occasionally as I still have trouble digesting it due to celiac malabsorption which is now so much better than it was a few years ago.

Any ideas why my labs may be out of range and what the UIBC, calculated TIBC, Transferrin Sat mean?
Platelets have been low for at least a year and doc said that is ITP (autoimmune). I also have autoimmune celiac, hasimoto's autoimmune thyroditis, and autoimmune addison's disease as well as high parathyroid hormones.
I posted on another board, and it was suggested that I ask on the anemia board.
Thank you for any information.
Robine

Snowgoose 02-15-2009 10:55 AM

Re: ferritin low, iron and B12 high, other labs off
 
I was diagnosed with hemochromatosis 3 years ago in 2006, and I only have one hemochromatosis gene -- H63D. Most doctors believe that people who only have one hemochromatosis gene are not at risk for developing hemochromatosis or iron overload. Because of that misconception, none of the doctors I saw over a period of 13 years were concerned that my blood tests and a liver biopsy indicated that I was accumulating and storing abnormal amounts of iron. Here's how my test results progressed:

1993:
Serum iron 267 (abnormally high)
Transferrin saturation 88 (abnormally high)
Ferritin 94 (normal)

1996 Liver Biopsy:
Iron in Liver Tissue 2087 (abnormally high)
Hepatic Iron Index 0.8 (normal)

2003:
Serum iron 277 (abnormally high)
Transferrin saturation 93 (abnormally high)
Ferritin 287 (normal)

2006:
Serum iron 255 (abnormally high)
Transferrin saturation 89 (abnormally high)
Ferritin 1494 (abnormally high)

2006 Liver Biopsy:
Iron in Liver Tissue 6156 (abnormally high)
Hepatic Iron Index 2.0 (abnormally high)

I strongly suggest that you request copies of your test results so that you can monitor any abnormalities. When my ferritin was tested at 1494, my primary care doctor didn't even tell me about it, and I never would have known my ferritin was high if I had not requested a copy of my lab tests. When I told my doctor I was alarmed about my high ferritin, she said, "There's nothing to be concerned about." I then went to a specialist (a gastroenterologist) who diagnosed me with hemochromatosis 4 months after my primary care doctor told me there was nothing to be concerned about.

The gastroenterologist ordered a liver biopsy, and then prescribed phlebotomy therapy to remove the excess iron from my body. After phlebotomy therapy, all of my blood tests returned to normal values, but I don't know if the iron was successfully removed from my liver.

However, getting rid of the iron with phlebotomies doesn't undo the damage already done by hemochromatosis. I have liver damage, but no tests have been done to see if any other organs were damaged by the iron. I have arthritis, especially at the base of my thumbs (which is a common site for arthritis in patients with hemochromatosis). I had premature menopause when I was 32 years old, which is known as hypogonadism and is another complication of hemochromatosis.

Donna/Snowgoose

robine27 02-15-2009 01:46 PM

Re: ferritin low, iron and B12 high, other labs off
 
Donna/Snowgoose, Thank you so much for the information. My hematologist did make a referral to a gastroenterologist. Appointment is April 9th as he is booked with appts until then. By then I will have the MRI of the liver, February labs and a follow up with the hematologist. My liver function tests so far are fine and she checks that every three months. I usually do get copies of all my labs as I see a few specialists which do not have access to the computer lab system where my primary is located, and the other specialists like to keep up with the labwork and not repeat anything that has already been done.

Did you have any symptoms as the iron was building up in your body? One thing I have noticed is that my skin is tan all over, and the palms of my hands and the bottoms of my feet look kind of orange colored a lot of the time.
I have some other symptoms but the crossover symptoms with the autoimmune diseases can be similar. My endocrinologist was puzzled why my tan color is getting more noticeable. I do have addison's disease but tanning should have disappeared after 18 months on cortisone replacement (and I don't think the orange color is part of the addison's tanning). Wondered about the orange color as iron rusts and is kind of orange sometimes and I think I heard that hemochromatosis deposits iron-described in one place as rust in the organs. Just curious.

Thank you again for taking the time to give me the information with lab details.
Robine

Snowgoose 02-15-2009 02:52 PM

Re: ferritin low, iron and B12 high, other labs off
 
As you probably know, hyperpigmentation of the skin is one of the symptoms of hemochromatosis/iron overload. My skin doesn't look tanned all over, but I have hundreds of brown spots on my skin.

I did have (and still have) palmar erythema (reddening of the palms of the hands and soles of the feet), which can be a symptom of hemochromatosis, but I think it can also be a symptom of liver damage and some other diseases/conditions. At one time, many years ago, the palms of my hands turned orange, and I rushed to the doctor. The doctor asked if I was taking beta carotene (a form of Vitamin A), and I said yes as a matter of fact I was. The doctor said my orange palms were a side effect of the beta carotene, so he said to stop taking it and the orange color would go away. I stopped taking it, and the orange color went away. But I still have red palms and soles.

Hemochromatosis can cause thyroid disease. I had a goiter that came and went, beginning in my early teens and throughout adulthood. No one noticed my goiter when I was a teen (but now I see it very obviously in some of my old photos), and as an adult my thyroid tests were sometimes abnormal and sometimes not, fluctuating between hypo, hyper, and normal. But I was never diagnosed with thyroid disease. When I developed a goiter again in 2006, my doctor said my thyroid gland should be removed. I had a total thyroidectomy, and the pathology report noted that my thyroid gland was brownish red in color. I had not been diagnosed with hemochromatosis at that point in time, but after I was diagnosed with hemochromatosis, I asked my doctor if the brownish red color of my thyroid was normal, and she said no, it's supposed to be pinkish red, not brownish red. I asked if the brownish coloring could have been caused by iron, and she said yes. Since iron causes inflammation, I assume my thyroid was being irritated and inflamed by iron, and that's why my thyroid blood tests fluctuated, and that's what caused the gland to swell (the goiter), in my opinion. The pathology report said that I had a benign goiter. I wish that I had never had my thyroid removed, because ever since then, I've had numerous additional problems and symptoms caused by not having a thyroid gland. For me, taking a thyroid hormone pill is not a good replacement for the vital functions of the thyroid gland.

Here's an article about a possible link between hemochromatosis and Hashimoto's thyroiditis:
[url]http://www.ncbi.nlm.nih.gov/pubmed/18299688[/url]

I also have an autoimmune disease called myasthenia gravis. I have no idea if hemochromatosis has anything to do with it. I also have severe osteoporosis. Hemochromatosis has been implicated in osteoporosis. I'm also hearing-impaired. Hemochromatosis has been implicated in hearing loss.

Almost every symptom of hemochromatosis can also be attributed to other diseases, so it's very hard, if not impossible, to determine what is actually caused by hemochromatosis. In all of the reading I've done about hemochromatosis, here is a list of the diseases and conditions it can cause (The list is incomplete. I keep adding to it when I discover new information in medical journal articles):

Adrenal Glands: Insufficiency

Arthritis: Chondrocalcinosis

Bones: Arthritis, Osteoporosis

Cancer: Liver (Hepatocellular carcinoma)

Diabetes Mellitus

Hearing Loss

Heart: Angina without coronary artery disease, Cardiomyopathy (Congestive and Restrictive), Heart Failure, Irregular heart rhythms, Pericarditis

Liver: Cancer, Cirrhosis, Enlargement, Fibrosis, Hepatitis, Liver Failure

Pancreas: Diabetes, Dysfunction

Sex Organs: Impotence, Premature Menopause

Skin: Bronze or Gray, Hyperpigmentation

Thyroid: "Thyroid gland involvement is manifest by thyroid tissue inflammation and fibrosis, with initial hyperthyroid function followed by low thyroid output. Unfortunately, hypothyroidism does not improve with treatment. It might even continue to worsen despite treatment." (I'm sorry, but I didn't keep a record of where I got that quote from.)

Donna/Snowgoose

Audrey-B 02-15-2009 03:20 PM

Re: ferritin low, iron and B12 high, other labs off
 
Hi Donna - wow, you have done some research!! The thing i noticed was that your ferretin was SO high which would indicate iron overload, yet robine's ferretin is low at only 28 yet you both have one gene found for the hemochromatosis. I find that unusual.

Robine - in your case i'm still curious about your high B12. I hope you get some answers to that as i can't find too much apart from what i posted on your thread on the thyroid board.

Donna - thyroid issues will most often flare up during major hormonal changes, such as teens, pregnancy and menopause, so it's not unusual that you should have had a goitre/thyroid issues way back then.

If a doctor had correctly assessed your situation back then and started you off on medication there is a very good likelyhood that your thyroid could have been saved and not be removed.

It's a shame doctors base their findings on usually TSH alone, rather than looking at the entire thyroid panel. This is how i went undiagnosed for 8 years, even though i had sky high thyroid antibodies. I had Hashimoto's back in 2000, yet was refused treatment by an Endo simply due to my TSH not being off the scale. I'm just lucky that my thyroid destruction appears to be a slow moving one.

FLFLOWERGIRL 02-15-2009 05:59 PM

Re: ferritin low, iron and B12 high, other labs off
 
Robine--Welcome to the boards! My DH has HH and double gene mutation. We were told that both of our children are carriers. When my son was tested his Internist said he did not have HH, but would have to be monitored every 5 years for this disorder. So, I would think that obviously you can begin to overload without 2 genes present according to what we were told.

Also, according to your labs they are consistent with iron overload, except for the ferritin, which throws me. A low transferrin can also be found in other conditions such as chronic disease, but I don't know much about that. When a serum ferritin and T-Sat % are both elevated along with normal Hgb (I think ferritin has to be over 200 for females) overload is likely, and can be treated. Perhaps this could be a beginning stage of iron overload. Your ferritin is low end normal.

In Iron overload the opposite of iron deficiency occurs in labs. With excessive iron TIBC tends to decrease, serum iron is high and these together result in a high T-Sat %. I still don't get the 28 ferritin iron store in containment. Perhaps this is from an overlapping symptom of Hashi's or something else that you may have.

What does your Hematologist think? I am very curious. I don't think that your iron is high enough to worry. My Hematologist told us that over 10 and under 1000 is the rule. Everyone has a different opinion. My husband is also treated through a GI doc for phlebotomy, organ checks and labs. His ferritin was almost 3,000 and is now 27 and we are told this is without damage. The GI doc said he didn't even need a liver biopsy because the MRI, CT and US are normal and all organs feel normal when palpitated. I'm sorry that you are dealing with so much. Best of luck to you. Keep us posted.

Snowgoose 02-15-2009 10:56 PM

Re: ferritin low, iron and B12 high, other labs off
 
Aubrey - In 1993 when it was first discovered that my serum iron was abnormally high, my ferritin was normal (as is Robine's). My serum iron remained abnormally high for the next 14 years until I received phlebotomy treatment for hemochromatosis in 2007. But my ferritin was rarely tested during those 14 years. Here are the lab results of my ferritin tests:

11/09/93: 94 (Normal)
10/31/96: 450 (High)
08/29/03: 287 (Borderline High/Normal)
11/16/04: 553 (High)
08/28/06: 1331 (High)

As you can see, my ferritin doubled from 2003 to 2004, and it more than doubled from 2004 to 2006. I believe that my ferritin dramatically increased in 2004 because from the time that I was diagnosed with premature menopause in 1983, I took hormones (hormone replacement therapy) and as a result, I had a period every month for 20 years until I stopped taking the hormones in 2003, at which time I stopped having periods. Periods are like phlebotomies -- they cause excess iron to leave the body. Once I stopped having periods, the iron rapidly accumulated in my body.

Perhaps Robine's ferritin is normal because she still has periods (I don't know if she does or not).

Since ferritin can be high due to reasons other than iron storage (such as inflammation), other tests should be done to confirm that iron storage exists. Those other tests include serum iron and transferrin saturation percent. From what I have read, transferrin saturation percent is the most reliable indicator of iron storage and hemochromatosis. My transferrin saturation percent was abnormally high from 1993 until I received phlebotomy treatment in 2007, and my transferrin saturation percent was high even when my ferritin was normal and even during the years that I was having periods.

Since most doctors rely on ferritin as an indicator of iron overload, women are not usually diagnosed with hemochromatosis until they are post-menopausal and their ferritin becomes so abnormal that it's impossible to ignore it (although my doctor ignored it).

Like me, Robine has high serum iron, high transferrin saturation percent, and one of the genes for hemochromatosis. I was not diagnosed with hemochromatosis until a second liver biopsy was done which confirmed that the iron in my liver had more than tripled since my first liver biopsy. Perhaps the deciding factor in Robine's diagnosis will be whether or not her MRI shows iron storage in her liver.

Donna/Snowgoose

robine27 02-16-2009 08:02 AM

Re: ferritin low, iron and B12 high, other labs off
 
Thanks to all for the detailed information. It gives me lots to think about and question before I see the hematologist on 2-27. I also looked up some of my old labs of which there are many. I did have a hysterectomy in 1986. Most of my life I was anemic as labs from 1990 show, even after the above surgery. Anemia most likely due to celiac undiagnosed at this time.

9-1990
RBC 4.5 (range 4.8-10.8)
Hematocrit 33.9 (range 37-47)
Hemoglobin 11.6 (range 12-16)
TSH (0.7) low (range 3.4-5.0) just interesting as I hadn't been diagnosed with Hasimoto's at this time. Range for TSH has changed since then.

In 2005
Ferritin 176 high (range 13-150)
TIBC 254 low (range 260-470)
Folate high says greater than 20 (range 2-20) No number given
Iron 75 (range 30-160)
Hemoglobin 13.6 (range 12-16)
Hematocrit 39.8 (range 36-48)
Vitamin B12 1129 high (range 240-900)
TSH 2.0 (range .27-4.2) still not diagnosed with Hashimoto's
Platelet Count 142 low (range 150-440) not yet diagnosed with ITP

8-2008
Iron 117 (range 35-150)
UIBC 100 low (range 126-382)
TIBC 216 low (range 250-450)
Transferrin Sat 54 (range 15-60)
Hematocrit 40 (range 36-46)
Hemoglobin 13.2 (range 12-16)
Ferritin 29 (range 5-204)

11-2008
FE (Iron) 155 high (range 35-150)
UIBC 48 low (range 126-382)
TIBC 202 low (range 250-450)
Transferrin Sat 77 high (range 15-60)
Hematocrit 41 (range 36-46)
Hemoglobin 13.7 (range 12-16)
Ferritin 29 (range 5-204)
Platelets 128 low (range 150-400)
TSH 0.35 (range 0.3.5-4.94) Endo MD wants TSH below 1.0

5 years ago celiac was diagnosed along with osteoporosis, 3 years ago hasimoto's diagnosed, 2 years ago addison's diagnosed, 1 year ago ITP diagnosed.
I think the malabsorption associated with celiac has probably affected iron absorption for a long time and has now improved considerably.

Now that absorption is much better my iron is creeping up, UIBC and TIBC both going down. Ferritin was up 4 years ago, and has been creeping down. Perhaps lower Ferritin is associated with hashi as suggested.

All my minerals and vitamins were far below normal 5 years ago due to celiac. I have been on some prescribed vitamins and intravenous infusions to bring things up. No iron given at all. No B12 in infusion either. B12 in vitamins is 600 mcg daily. Docs are not worried about B12 elevation due to supplements. I do take prescription pancreatic enzymes to improve absorption so that may influence things as well. When I see the nutrition doc in March I will see if he wants to check Vitamin A levels again.

Audrey- Thanks for the information on the thyroid board. I didn't think about the anemia board as my iron, etc was on the high end except for ferritin.

Donna: I did check my vitamins and there is more than the usual of vitamin A - 3,200IU in one, 3,700 IU in the other. I think 4000IU is the daily recommendation normally. Since they are multi vitamins and eye vitamins (due to extreme night blindness and some eye swelling of cornea and macular with extremely dry eyes when malabsorption was at its worst and preventing me from driving in the dark and on bright or rainy days for about 6 months), I will ask my nutrition doc about dropping the dose to half. All the eye problems have resolved with the vitamins so don't want to stop vitamins all together. I could never tolerate vitamins before my doc recommended the current vitamin supplements and B12 is included with all the other things I need. I also drink carrot juice twice a day so will try once a day. I'm sure you are right that the orange color in palms and bottom of feet is from increased vitamin A. Thank you.

Donna: Did the MRI of the liver include a scan with dye or does the iron show up because the MRI picks it up as a metal type substance?

FLFlowergirl: My hematologist wants the MRI to check on iron damage to the liver. I had an MRi of abdomen 4 years ago and liver was normal at that time. She and my endocrinologist both keep wondering why after being on a very strict gluten free diet my other organs are being damaged so have ruled out all the other autoimmune diseases with a rheumatologist in Boston (ANA is also mildly elevated). She mentioned phlebotomy if numbers continue to be up even if MRI is negative, to prevent damage to liver.

FLFlowergirl, what is the US your DH had? What does the gastroenterologist do to check organs? Also which tests did your children have to screen for hemochromatosis? My daughters both need to be tested but would like to tell them which tests to have-probably gene tests and all the iron tests. At this point they are both anemic.

Thanks again to all for taking the time to respond in detail to my questions. It is really helping me put some of the pieces together in this ongoing puzzle.
Enjoy the day!

Robine

Snowgoose 02-16-2009 08:57 AM

Re: ferritin low, iron and B12 high, other labs off
 
Robine - I think your orange palms might be from the carrot juice because it contains beta carotene. The Vitamin A in your multivitamin supplements probably is not beta carotene, so it wouldn't cause orange palms, and therefore you wouldn't need to reduce the supplemental Vitamin A that you're taking. Just my opinion.

Vitamin C increases intestinal absorption of iron. If by chance you're taking megadoses of Vitamin C, it might be advisable not to do that.

I didn't have an MRI to detect iron in my liver, so I don't know if they use contrast dye. Some doctors still think that liver biopsy is the best procedure to do, and I happened to have one of those doctors.

This is from a very interesting article about hemochromatosis, and it talks about liver biopsies and MRIs to detect iron in the liver:

"Once viewed as the standard procedure for diagnosing hemochromatosis, liver biopsy is increasingly being seen as unsuitable for this purpose because its results are frequently normal at early stages of the disease. Heavily iron-laden liver specimens taken at biopsy certainly provide meaningful information for diagnosing iron overload disease; however, as the pathophysiology of hemochromatosis shows, the earlier a biopsy is done in the disease, the more likely are the results to be normal or equivocal. For instance, half of liver biopsies done in presymptomatic cases have shown normal results. Even in symptomatic cases, about 8% of liver biopsies do not produce diagnostic results (ie, grade 3 or 4 when Perls' stain is used). Thus, liver biopsy results and their derivative measures (eg, the Hepatic Iron Index) are often misleadingly normal at precisely the stages of hemochromatosis where therapeutic opportunity is greatest.

"The same logic applies to use of magnetic resonance imaging (MRI) and magnetic susceptometry (SQUID) to evaluate liver iron stores because these techniques also show normal stores of iron in the liver early in the disease. No matter how sophisticated the approach, any diagnostic technique focused on liver iron stores is limited to diagnosis of advanced cases only; worse yet, early cases will predictably be missed. On the other hand, because hepatoma is a potential outcome of untreated hemochromatosis, those who favor liver biopsy argue that it has a role in demonstrating cirrhosis with its implications for development of hepatocellular carcinoma. Others see little purpose in attempting this prediction."

Source: [url]http://xnet.kp.org/permanentejournal/winter99pj/hemochromatosis.html[/url]

It sounds like you have a good hematologist since she mentioned having you get phlebotomies even if your MRI is negative.

Donna/Snowgoose

FLFLOWERGIRL 02-16-2009 05:12 PM

Re: ferritin low, iron and B12 high, other labs off
 
FLFlowergirl: My hematologist wants the MRI to check on iron damage to the liver. I had an MRi of abdomen 4 years ago and liver was normal at that time. She and my endocrinologist both keep wondering why after being on a very strict gluten free diet my other organs are being damaged so have ruled out all the other autoimmune diseases with a rheumatologist in Boston (ANA is also mildly elevated). She mentioned phlebotomy if numbers continue to be up even if MRI is negative, to prevent damage to liver.

FLFlowergirl, what is the US your DH had? What does the gastroenterologist do to check organs? Also which tests did your children have to screen for hemochromatosis? My daughters both need to be tested but would like to tell them which tests to have-probably gene tests and all the iron tests. At this point they are both anemic.


Robine--I'm glad that you have other AI things ruled out as a cause. Your ANA can be slightly elevated from Hashi's.

I also have read that until your ferritin (for women) has exceeded 200 they would not prescribe Phlebotomy, I'm not sure if that's correct though. Also, after iron stores are filled this is when iron overload happens and then damage occurs to organs. If you haven't had ~high~ ferritin numbers I don't think that you have anything to worry about, but I know it is very concerning.

My husband's doctor does the US ultra sound first then CT scan and then MRI in this order. There was no damage shown in any organs. His ferritin is 27 and they don't want him to go monthly anymore, they have prescribed every 4 months. They don't want to make you anemic. The doc said that it is different for each person as far as the rate of unloading iron. He has one patient that he cannot get to lower the ferritin after years. In my husband's case it took two years to unload. The ferritin unloads at a faster rate if there is organ damage also.

For my children it was recommended to have first a Ferritin then Iron panel and DNA testing in this order. The DNA tests were assays to detect the two mutations C282Y and H63D that are commonly associated with HH.

IMO a GI doc is the best to see for this because they handle these cases on a very regular basis. My Hematologist said that my husband should stay with the GI doc for care when we asked who he should be seeing for this. He is monitored very closely through blood tests and phone messages. He only has to go in once in a while. The doc said at this point he doesn't even recommend another MRI. Hope you get answers soon.

Snowgoose 02-16-2009 08:42 PM

Re: ferritin low, iron and B12 high, other labs off
 
FLFlowergirl - You wrote: "The ferritin unloads at a faster rate if there is organ damage also." Do you know why ferritin would unload faster if there's organ damage? Do you recall where you got this information? I'd like to read about it, since it only took 5 months of once-a-week phlebotomies for my ferritin to go down to 21.

Donna/Snowgoose

Audrey-B 02-17-2009 03:54 AM

Re: ferritin low, iron and B12 high, other labs off
 
Robine - no problem, it's good to sometimes post on other sections of the healthboards as you never know what you can find out. I sometimes forget there are other sections aside from anemia/thyroid which can help with my personal situation.

Regarding the thryoid, i learnt something interesting recently and reading one of your earlier posts on this thread reminded me of it. You mentioned your high calcium levels and that reminded me of the fact that low selenium and high calcium levels can result in underactive thyroid. Another friend has an underactive thyroid and coincidentally her calcium is high. I've not had my calcium tested but will be at next test as i'm very curious. I am on selenium drops daily and i introduced Brazil nuts into my diet a while back.

I've also came across the information that hormonal imbalances can be mineral imbalances eg: magnesium, zinc, calcium, manganese and chromium and my friend today said her naturopath said to add tyrosine to the list.

You mentioned being on digestive enzymes, that is the same as me. I also found out recently that Vit A is important as it fascilitates efficient absorption of nutrients by strenthening the lining of the digestive tract. The thyroid gland needs Vit A to produced thyroxin, which in turn is the thyroid hormone that helps the thyroid absorb iodine. Think i'll be adding Vit A to my things to be tested.

Seems like everything revolves around hormones and digestion :)

FLFLOWERGIRL 02-17-2009 10:45 AM

Re: ferritin low, iron and B12 high, other labs off
 
Hi Donna--Actually, that bit of information I have read. And it did concern me, I will try to find it, but don't know how successful that will be. Our GI stresses how different the patterns for unloading are for individuals. Don't be too concerned about that. Some people are quicker than others. The more aggressive you are in the beginning the faster also. I think they started out too slow with my husband and then increased this, that's when he made progress. So one person cannot really compare to another. Your story is very interesting. I will keep this in mind for my own children.

FLFLOWERGIRL 02-18-2009 09:09 AM

Re: ferritin low, iron and B12 high, other labs off
 
Audrey--Have you ever measured the antibodies before taking selenium and after? I was told to try it, but you know how I am with supplements, I didn't do it :). I was wondering if you know if it lowers them successfully. My doc will not retest antibodies. Thanks. Be well.

Audrey-B 02-19-2009 02:27 AM

Re: ferritin low, iron and B12 high, other labs off
 
Hi FLFLOWERGIRL - when i visited the Trichologist for my hair shedding, before i knew of the Hashimoto's, he checked my selenium levels via a blood test and it came up that they were good. when i visited my thyroid doctor later on, he put me on selenium drops and i told him my selenium levels were ok. He then went on to say that blood tests of selenium were not accurate and often came up as being high when you were likely actually a lot lower. He said you can safely take a small daily dose each day for up to 5 years before it would become "too much", as not enough selenium can be as bad as too much.

I get my antibodies tested every 6 weeks when i get my other thyroid tests done. My Anti Thyroglobulin did begin falling, but then after my stress it rose. My Anti thyroid Peroxidase is over 1,300 but i don't know how much by as the lab stops counting after 1,300.

I do know that on the thyroid board there is a poster who feels that selenium has helped her, her mother and her aunties, but then again i guess everybody is an individual and that particular poster takes certain other supplements which she feels benefits her.

I'm going to have a mineral balance test to see how my various minerals are doing as a mineral imbalance can lead to hormone imbalance too. My main worry is my estrogen excess. I was looking at herbs, but a lot of herbs out there which correct hormones actually can make estrogen go higher and that's not what i want.


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