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Old 09-06-2011, 10:52 PM   #1
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Question Thalassemia Carrier

Dear all,

What is the affect of a man who is thalassemia-free marrying a woman who is a thalassemia-carrier? Will their child be a thalassemia-carrier as well? What are the odds of this happening (in percentage)?

Appreciate your immediate response

Thank you very much

 
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Old 09-07-2011, 12:14 AM   #2
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Re: Thalassemia Carrier

I believe your chances are that 1 out of 4 or 25% of your children will be carriers only. Both parents must pass the defect for a child to be affected by the disease.

Last edited by anajam; 09-07-2011 at 12:23 AM. Reason: typo

 
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Old 09-07-2011, 01:16 AM   #3
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Re: Thalassemia Carrier

Dear Anajam,

Thank you very much for your reply.

Hence, for this case, the worse-case-scenario is that the child will be a thalasemia-carrier and the chances are 25%.

Thus, this should not be and issue should it?

Thank you

 
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Old 09-08-2011, 09:37 PM   #4
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Re: Thalassemia Carrier

That is my understanding. It is always wise to check with a health professional. Every blessing to you.

 
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Old 09-08-2011, 10:39 PM   #5
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Re: Thalassemia Carrier

Actually it is a 50% chance that your child will be a carrier. The carrier has one normal gene and one Thalassemia gene, and the child will inherit one or the other. The child will definitely NOT have Thalassemia.

IF two carriers marry, there is a 25% chance the child will inherit the disease.

 
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Old 09-08-2011, 11:18 PM   #6
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Re: Thalassemia Carrier

Thank you for giving the correct information. I incorrectly did a cross using two carriers when izhar stated that he was not a carrier at all.

 
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Old 09-09-2011, 09:40 PM   #7
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Re: Thalassemia Carrier

Hello Everyone, I have Thalassemia too, as does my mom. I don't know if my dad has it or not. Regardless, would he have to be a carrier for me to have it? Both my parents are from the Mediterranean and I am an only child. Thanks in advance for any answers...janiee

 
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Old 09-09-2011, 11:05 PM   #8
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Re: Thalassemia Carrier

Thalassemia Minor causes some anemia problems, but many people with it are asymptomatic carriers. It can be inherited from one parent.

Thalassemia Major must be inherited from both parents. The Major form is a serious genetic disease which can result in a host of nasty complications.

 
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Old 09-10-2011, 10:12 PM   #9
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Re: Thalassemia Carrier

janewhite, Thanks a lot for the info!! My doc said that when you have Thalassemia (minor) you don't feel the fatigue much when you are young, but as you age it becomes more noticable. I surely do feel it now, though I also have Fibro. ...janiee

 
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