I still drink wine or a beer once in a while and I'm on Wellbutrin in the AM and Lexapro in the PM. I had to cut back the amount I drank because it would hit me really hard and I would sort of black out!! That was scary! That had never happened to me before. I could only remember bits and pieces of the evening. My boyfriend is always with me when I drink because he knows that I tend to get a little loopy if I have more than 2 drinks...

(on the bright side I am cheap date now LoL!) In moderation I am fine. One glass should be OK but remember that it will feel more like 2 or 3 if you are medicated so be careful! And of course check with your doctor first. Good luck!