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View Full Version : biochemistry of supplement- evening primrose oil


 

 

 
fishyfishy
08-01-2002, 05:10 AM
Hi there,
Does anybody happen to know about the evening primrose oil? or even gamma linolenic acid {GLA}? its taken or rather recommended for acne n most of the time, for PMS. i would really like to find out the pathway it takes once taken into the body, the enzymes involved n how it eventually bring about the expected changes in the body....Even any recommendation for books or libraries would help alot...cos i'm really desperate for an answer! tanx!

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Jay Tor
08-02-2002, 08:57 PM
Trying doing a search on a med/sci engine [e.g. scirus].

Journal: Prostaglandins, Leukotrienes and Essential Fatty Acids, Feb 2000 [Article on GLA];

Journal of Investigative Dermatology, Apr 1995 [Prostaglandins of the E series (PGE) inhibit the migration and function of PMN and MNC. Both the PGE-agonist misoprostol and gamma-linoleic acid can lead to an improvement in inflammatory skin.]

Another heading to investigate is physiologic lipids e.g. eicosanoids [plus, di- and tri-enoic acids]; this is a major section in any human biochem text.

fishyfishy
08-05-2002, 02:53 PM
tanx lots! actualy im a first year student in NTU (singapore); majoring in biology. was given the assignment to find out about diet supplements n had picked EPO. the info u provided certainly helped=) sorry but can i juat ask 1 question? izzit tt EPO supplies us with GLA, whereas linoleic acid supplies us with arachidonic acid? both of which are precursors of prostaglandins...


NB: really tanx 4 ur attention to my questions

Jay Tor
08-05-2002, 07:21 PM
Sorry. But if this is a school assignment, I'm not sure I should be volunteering any answers. Plus, it's complicated!

Look up lipid synthesis, or metabolism of unsaturated fatty acids & eicosanoids [i.e. eicosapentaeoic acid and series 3 prostaglandins]. Harper's Biochemistry 1996 Ed. has an entire chapter on this.

fishyfishy
08-06-2002, 09:54 AM
tanx!!!=)





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