Hi...I am new to this board...very glad I found it! I was wondering if anyone has had therapy which included Temazolamide and or Thalidomide? If you have, could you let me know how it was, any side effects, etc? My father,m 81yrs, was diagnosed with Satge IV melanoma, upper left arm, in Febuary, 2003. It was fully resected, margins were clean, sentinal node biopsy done and no positive nodes at all!! We were extremely happy to say the least!!! His Oncologist suggested a yearly CT Scan and no other treatment needed at that time. A week ago, my father, told me about a mass he had on upper chest area. Immediately we went to the surgeon, whom by the looks and characteristics of this mass said it looks like melanoma again, will know for sure after surgery nect week. That day we had a CT of abdomen, pelvis, and thorax. Chest is good!!! But liver showed possible mets to the liver. So this leads me here and my question about the therapy which includes Temazolamide and or Thalidomide, which I have been told is being used to treat this. Sorry this post is a bit long....am a bit freaked by this...guess needed to vent a bit!!! So if anyone has gone through this and or other treatment for malignant melanoma please respond!! I'd be very greatfull!! :)