I have a question about this. I had been on just plain Glyburide and I guess with all the stree my sugars have been rising slowly. I asked for the time release Glyburide and it seems to help a great deal. But I seem to suddenly be putting on weight little by little. I have never had this problem, wonder if any of you know about this. Or have noticed weight gain with this.
I also haven't been walking much if at all due to hips. (arthritis) Thanks
D-2
Metamorphine-1000mg
Glyburide-5mg

Is no one in here on Glyburide????????? :eek:

i have used glyburide. It seemed to help with my blood sugar, but i have never used the xl. I have read that this product can put weight on. I put on weight, however I am on paxil cr so that too can do it. We had to decide what we were going to try to change to see what could be doign it and we decided to do the glyburide. The doctor had changed me to glucophage and avandia instead, but they dont seem to be controling my sugar as well and I am thinking of going back to glyberide.

i have been on glyburide 20 mg a day and yes there is some weight gain with it but my weight gain is with my neurotin the best i can suggest is to keep it on a low fat/carb diet that should help

Thank you for posting, I was begining to think I was all alone here.
So there is weight gain, I had no idea but do notice the weight on my tummy.
The XL is time released and it does seem to work better for me with the glucophage. Thank you :)

well mine is not xl but it is metformin 500 mg i take 2 each am and 2 each pm

did you notice the weight gain with the extended release? Or the regular one?

im on the regular one so that would be yes on the regular one

I had been on the regular Glyburide for several months along with Metformin and I didn't have a problem with weight at all. When I switched to the time release (Glyburide xl) I found myself eating and hungry quite a bit. I noticed the weight gain then.
Just wasn't sure if it was nerves and stress or the xl, now I think it is the xl so I am watching it better.

I've been on it since about 1987, no problems. I like it. (a/k/a Glucatrol 10 XL, right?)

The limit is supposed to be two a day, in the morning, but my first doctor had me on three, one in the evening, with no ill effects. My present doctor doesn't.

I had some muscle problems after years of metformin/glucophage, which is discussed in another thread here. Had a buildup, I guess. He had me on a lot of it.