TATS
06-11-2004, 03:37 PM
hey shore man glad to read you and pump are doing well.i'm going to my pm doc on mon.and need some advice?i'm taking 90mg.morphine E.R.daily and roxi 30mg.up to 4 times as needed for b.t.pain.i dont have insurance so i'm limited by expense.the doc wanted me on oxi-cot but i dont have 600 plus.my problem is hepC.i tried methadone 120mg daily but it made my liver spike.i need somthing cheap but yet strong?is dulidid a drug that would fall into this catogory?does it work oraly or is it lost when done that way?is the liver the main organ that does all the work besides the brain?also ;i have addisons disease this means my heart runs slow i.e.morphine literature stess's to be carful when addministered with addisons.shore its taken me awhile to post (personal problems) so if you could think this over and drop me a line i would be thankful.
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Shoreline
06-11-2004, 04:09 PM
Hi Tats, Although I would prefer Dilaudid PCA "IV' over any other med for post op pain, when delivered orally it's not nearly as effective, It's half life is shorter than morphine and duration was limeted to bearly 3 hours regardless of doseage.
Roxicodone is mighty expensive especially if you take 4 a day. Short acting morphine is just as cheap as generic Dilauadid, I get 100 30mg generic MSIR for 27 bucks at Sams club with the Peoples prescription plan. But you loose the benefit of using multiple opiates to cover a broader range of receptors. That 7 bucks a month does pay for itself over and over. The PPP is managed by Advanced PCS which is the largest prescription drug insurance co in the country, so the discounts are real. It dropped my meth from 90 bucks to 60 bucks.
If you tolerate the LA morphine, using MSIR "generic" for BT would seem to make sense but I need to take a look at the contraindications and research addisons a bit.
I'll get back to ya though, Take care, Dave
Levodromoran may be another alternative but I need to check that too.
Roxicodone is mighty expensive especially if you take 4 a day. Short acting morphine is just as cheap as generic Dilauadid, I get 100 30mg generic MSIR for 27 bucks at Sams club with the Peoples prescription plan. But you loose the benefit of using multiple opiates to cover a broader range of receptors. That 7 bucks a month does pay for itself over and over. The PPP is managed by Advanced PCS which is the largest prescription drug insurance co in the country, so the discounts are real. It dropped my meth from 90 bucks to 60 bucks.
If you tolerate the LA morphine, using MSIR "generic" for BT would seem to make sense but I need to take a look at the contraindications and research addisons a bit.
I'll get back to ya though, Take care, Dave
Levodromoran may be another alternative but I need to check that too.
Shoreline
06-11-2004, 04:15 PM
Hi Tats, Although I would prefer Dilaudid PCA "IV' over any other med for post op pain, when delivered orally it's not nearly as effective, It's half life is shorter than morphine and duration was limited to barely 3 hours regardless of doseage. But you may find you resppond better to oral Hydromorph than I. I would need to check it with addisons too.
Roxicodone is mighty expensive especially if you take 4 a day. Short acting morphine is just as cheap as generic Dilauadid, I get 100 30mg generic MSIR for 27 bucks at Sams club with the Peoples prescription plan. But you loose the benefit of using multiple opiates to cover a broader range of receptors. Oxy works particularly well on visceral pain.
That 7 bucks a month does pay for itself over and over. The PPP is managed by Advanced PCS which is the largest prescription drug insurance co in the country, so the discounts are real. It dropped my meth from 90 bucks to 60 bucks.
It may also help to know what your pain generator is, Visceral, Somatic or Neuro
If you tolerate the LA morphine, using MSIR "generic" for BT would seem to make sense but I need to take a look at the contraindications and research addisons a bit.
I'll get back to ya though, Take care, Dave
Levodromoran may be another alternative but I need to check that too.
Roxicodone is mighty expensive especially if you take 4 a day. Short acting morphine is just as cheap as generic Dilauadid, I get 100 30mg generic MSIR for 27 bucks at Sams club with the Peoples prescription plan. But you loose the benefit of using multiple opiates to cover a broader range of receptors. Oxy works particularly well on visceral pain.
That 7 bucks a month does pay for itself over and over. The PPP is managed by Advanced PCS which is the largest prescription drug insurance co in the country, so the discounts are real. It dropped my meth from 90 bucks to 60 bucks.
It may also help to know what your pain generator is, Visceral, Somatic or Neuro
If you tolerate the LA morphine, using MSIR "generic" for BT would seem to make sense but I need to take a look at the contraindications and research addisons a bit.
I'll get back to ya though, Take care, Dave
Levodromoran may be another alternative but I need to check that too.
TATS
06-12-2004, 02:14 PM
hi shore ,this is a drag i wrote you this morning and thanked you for getting back to me so soon .then i pressed submit reply and poof it disapears?i dont see it any where? so i'll send this short note and see where it goes?
Shoreline
06-12-2004, 02:26 PM
Hey Tats, I'm online now if you can answerabout your pain generator, I kept loosing posts yesterday too and now I see I have duplicated the one that made it. I'm not sure what the glitch is , But if you can tell me about your pain that would be great.
Although I have only had the pump for 10 days it's making a difference, My head is so much cleaer, It's amazing what .1 mgs delivered IT every hour can do, It's not metabolized by your liver and if any exxcess is, the doseage would be so low I couldn't imagine it causing any liver problem. You may want to start researching the pump. The synchromed 11 is now beingtest marketed, thay make a thinner pump and one the same size withat holds enough meds for up to 6 months.
It took 3 years of research and 2 seperate trials to convjnce me this was the right thing to do. I'm not sugesting you jump to a pump without great consideration. But IT meds are basically 300 times stronger than oral meds, The refills are coverd by medicare, which is my only insurance, so I'll be saving the money spent on meth and hopefully save money on BT meds.They can even put baclofin for spasm or spasticity into the pump along with numbing agents.
Personally I would love to go back to Roxi for BT but I can't fork out 150-200 bucks a month for 100 30mg pills.
I'll be doing some checking on addisons and come back at take a look at your response. Take care, Dave
Although I have only had the pump for 10 days it's making a difference, My head is so much cleaer, It's amazing what .1 mgs delivered IT every hour can do, It's not metabolized by your liver and if any exxcess is, the doseage would be so low I couldn't imagine it causing any liver problem. You may want to start researching the pump. The synchromed 11 is now beingtest marketed, thay make a thinner pump and one the same size withat holds enough meds for up to 6 months.
It took 3 years of research and 2 seperate trials to convjnce me this was the right thing to do. I'm not sugesting you jump to a pump without great consideration. But IT meds are basically 300 times stronger than oral meds, The refills are coverd by medicare, which is my only insurance, so I'll be saving the money spent on meth and hopefully save money on BT meds.They can even put baclofin for spasm or spasticity into the pump along with numbing agents.
Personally I would love to go back to Roxi for BT but I can't fork out 150-200 bucks a month for 100 30mg pills.
I'll be doing some checking on addisons and come back at take a look at your response. Take care, Dave
TATS
06-12-2004, 02:50 PM
i didnt press preview post 1st.da?will here it goes again although ,not word for word.thanks for getting back and turning me on to PPP i'll be talking to them on monday.ive been in 3 auto accidents the last one was in 96.......i went to pt and some how every thing was ok.then 2 yrs ago i picked up a big bag of dog food .the next day couldnt walk and had to use a wheelchair for a week or two.MRI results 2 hern. buldging disc's and the one closes to my tail bone had no fluid- exiting on left side.both legs are numb with nerve pain the left side is real bad.my records are at my docs and i'm not very good with med. terms.i had so much to say this morning but now i can feel the fatigue starting.shore is there any drug that works on pain and not my liver?i need to lay down i'll post this and get back to you thanks again.
TATS
06-13-2004, 09:43 PM
hey shore hows it going brother?had a bad day yesterday forgot to take my meds for the addisons and started shaking like a crap game in a bad alley.steroid wd is a drag and it kicks my ***.i just reread my urgent requests and saw you answered with the pump,witch some day i'll go that way?sorry i sounded so urgent like you dont have a ton on your mind.hope your adjusting?i see my doc tommrow and what ever he gives me well do,hope fully by next month i'll have it together ie files and the correct termenology.another reson i was upset yesterday ,i saw my #'s ALT,ASTand they tripled.my VA doc put me on testostrine(spelling)and in the lit. it says will mess up liver #'s......my #were low on methadome compaired to testost.what a drag it didnt make me feel any better just stressed me out the worse thing for adissinon's.thanks for the time Dave take it slow and stay cool......Tats
Shoreline
06-15-2004, 12:14 PM
Hey Tats, My Testosterone dropped like a rock when I took meth but rebounded once on morphine. I wish I could answer the question for you but most opiates are processed by the liver through the P450 cytochrome enzyme. The more meds you take that use this route of elimination the more stress it puts on your liver.
The advantage of Intrathecal meds is that the dosage is so miniscule that In theory it should cause virtually no Liver function problems. The dose my pump is presently set at is .1mgs of morphine deleivered per hour or 1/10th of a ML. It doesn't sound like enough to even whet your finger tip but it's 1/600th the amount of an oral dose.
Honestly, I think I'm over my head when I start adding specific diseases into the equation. It would take quite a while to research addisons although I'm interested in what the disease is, effects etc. I just don't feel comfortable giving medicinal advice when I don't have the knowledge to understand all the contra-indications and suttle ramifications of this illness.
I'm also going through quite a mess at home right now with my wife, daughter and finances,and having some problems with post surgery infectionto top things off, so I'm limited in my abilty to research as I'm watching my wife pack up every valuable in the house.
I think I just need to admit I can't really answer your question.. I do hope your doc is able to figure out what the best med and what would cause the least stress on your liver, but I need to back off and admit when I'm over my head.
I'm sorry I couldn't be of more help. There is a great site called "centerwatch," It lists every new drug in development by disease or name of drug that's presently in clinical trials. I and many other are watching Prialt, the cone snail toxin being tested in IT pumps for severe pain. You may find new drugs are being worked on for addissons' in Clinical trials, There has to be a better way than steroids, if your not interested in being the guinea pig and participating in the trial you can watch the advancement of the meds for this condition by monitoring that site. What stage their at, what they have learned so far, side effects, route of elimination, etc.
I do wish you the best. Take care, Dave
The advantage of Intrathecal meds is that the dosage is so miniscule that In theory it should cause virtually no Liver function problems. The dose my pump is presently set at is .1mgs of morphine deleivered per hour or 1/10th of a ML. It doesn't sound like enough to even whet your finger tip but it's 1/600th the amount of an oral dose.
Honestly, I think I'm over my head when I start adding specific diseases into the equation. It would take quite a while to research addisons although I'm interested in what the disease is, effects etc. I just don't feel comfortable giving medicinal advice when I don't have the knowledge to understand all the contra-indications and suttle ramifications of this illness.
I'm also going through quite a mess at home right now with my wife, daughter and finances,and having some problems with post surgery infectionto top things off, so I'm limited in my abilty to research as I'm watching my wife pack up every valuable in the house.
I think I just need to admit I can't really answer your question.. I do hope your doc is able to figure out what the best med and what would cause the least stress on your liver, but I need to back off and admit when I'm over my head.
I'm sorry I couldn't be of more help. There is a great site called "centerwatch," It lists every new drug in development by disease or name of drug that's presently in clinical trials. I and many other are watching Prialt, the cone snail toxin being tested in IT pumps for severe pain. You may find new drugs are being worked on for addissons' in Clinical trials, There has to be a better way than steroids, if your not interested in being the guinea pig and participating in the trial you can watch the advancement of the meds for this condition by monitoring that site. What stage their at, what they have learned so far, side effects, route of elimination, etc.
I do wish you the best. Take care, Dave
TATS
06-16-2004, 03:39 PM
Hi shore,thanks for all your help, in the 8 months ive been reading this board you have educated me to so much.......at times people forget your just a guy who has problems like everybody else.i hope you never feel used up being in such demand ,but you are the man in this area.at times you must feel overwhelmed by demands?nothing is more important then whats at home and that is worth the extra time to patch up.so you take care man and i'll be reading and taking notes .once again thanks,tats