Last October, I was diagnosed with depression. They were quick to put me on antidepressants, and they put me on Zoloft - thus the thread title.

At first, it worked like a charm. I even lost 20 pounds, very rapidly. I'm talking a month or 2 rapidly.

But in January the effects just stopped coming. I even started gaining weight again.

And this was just an endless cycle, sometimes it would work like a charm, others it would just not work.

They've upped my dosage from 20 to 50, 50 to 75, and now 75 to 100. I just don't feel like this is really right for me.

I'm afraid to go up to 200mg, and I'm also afraid to admit it's not working very well.

Should I just stop taking the medicine alltogether, or keep taking it because it might just be me, or what?

Thanks for any help you might offer.

-Cinder

The effect of Zoloft (or any antidepressent) does start to wear off (for most people), unfortunately. I wouldn't want to take more than 100 mg./day myself, because it was a serious medication. Perhaps you can try a different SSRI? Is there anything else that helps your depression (exercise, eating healthy--not a lot of processed foods, meditation, etc.?) I agree with you that staying on an antidepressent long-term (unless a very low dose) and continuing to up the dose isn't the best of ideas, but I'm not sure what will be your solution :(