I was once on Zoloft about five years ago for some depression i was having and it seemed to work oky for me but with a few side effects I didn't care for.well now my depression came back big time about a year ago and my doc wanted to try Lexapro this time around as he said it did not have as many of the side effects of the zoloft.wwll, i have been on Lexapro for well over a year now and it really helped quite a bit.But after about the year mark on it, and because of certain bad things that have happened in my life, my depression started to come back in a really big way.i went to my doc and he just raised my dosage and within about a week at the higher dose, i am sooo much better.i think the Lexapro is one of the better anti Ds out there and it definitely has less side effects.But keep in mind that just because a certain anti D has worked for some it may not work for all in the same way.So if this does not appear to be helping you, please talk to your doc about trying another one.Sometimes you have to try a few different ones at different doses to find the one that actually works for you.just hang in there and have a little patience and don't be afraid to try another med if the Lexapro does not work for you.marcia