Snuggles2u
03-10-2001, 07:58 PM
Can HPV cause cancer of the rectum or anus?
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View Full Version : just a little question
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Snuggles2u 03-10-2001, 07:58 PM Can HPV cause cancer of the rectum or anus? Snuggles2u 04-10-2001, 06:06 PM since no one could ansewer my question, I finally found out on my own what HPV can do to the anal area. from this article its from 1996, but it has some good information: http://www.actupgg.org/BAR/art0021.html To cut and paste the answer to my question here it is: Link to cancer Warts can progress to more serious conditions, such as cervical and anorectal carcinoma. Upon biopsy, warts frequently show early signs of dysplasia (for example, Bowenoid papulosis). Dysplasia, the medical term for abnormal cell growth, can be viewed as a spectrum, starting with normal cells on one end and dysplasia grades one through three representing increasingly severe abnormalities. Warts represent very mild dysplasia, while some sources believe that grade 3 dysplasia characterizes anal cancer. Dysplasia involving the anus or cervix is sometimes called anal intraepithelial neoplasia (AIN) or cervical intraepithelial neoplasia (CIN), respectively. In the general population, anal cancer is more common among women than men. Explanations include receptive anal intercourse and migration of HPV from the cervix. Women with a history of cervical dysplasia or cancer are at increased risk for anal dysplasia. In the United States, the anal cancer rates are rising at 2.0% per year among women and 2.3% per year among men. In the San Francisco Bay area, the incidence of anal cancer among single never-married men increased seven-fold between 1973 and 1989. Other studies have detected as much as a forty-fold increase in incidence. At present, anal examinations are only performed in response to a specific patient complaint: pain, bleeding, visible warts, etc. No equivalent to the routine gynecological exam, which includes manual examination and cervical cancer screening, exists. Cervical cancer screening, also known as the Pap smear, has reduced the incidence of invasive cervical carcinoma by 80% compared with 1950 levels. By detecting abnormalities early, physicians can effectively treat them, preventing progression to invasive cervical cancer, a condition that frequently carries a grim prognosis. Many researchers believe that routine screening of men and women who have a history of genital warts, cervical dysplasia or receptive anal intercourse, or who are HIV-positive, would help prevent anal cancer. The cervical pap smear can be easily adapted to anal screening. The physician inserts a moist Dacron swab into the rectum then simultaneously rotates and withdraws it while placing pressure on the anal canal. The swab is then smeared on a slide, fixed (preserved) with alcohol, and sent off for analysis. If abnormalities are found, the physician would insert an anoscope to examine and potentially biopsy any lesions. Warts and dysplasia would then be treated initially and as they recur. Left untreated, warts will continue to spread, increasing the risk of cancer. For both aesthetic and health reasons, it is important that warts be aggressively treated. Upon visual examination using an anoscope or sigmoidoscope, anal dysplasia is frequently mistaken for anal warts, and treated using the same methods. |
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