After suffering for the last 5 years with migraine headaches 3-4 times a week, and after trying mega doses of riboflavin, massage therapy, diet changes, lots of water to ward off dehydration which sometimes causes migraines, large doses of calcium, etc., I finally went the medication route and am now on propranolol. It is a beta blocker and is used to treat high blood pressure, and it has changed my life. I rarely get a headache, and if I do, I take one ibuprofen and am fine for the rest of the day, whereas before I took at least 3 at a time for minimal relief. I can be totally busy and stressed out and still not have a headache. I take 40mg twice a day. I started out with 20mg twice a day, and that almost worked, so the doctor upped it to 40mg 3 times a day and that was too much--it lowered my blood pressure too much. This present dosage now seems to be about right for me, although on occasion I feel light-headed, so only take 1/2 a tablet, and that seems to be fine. Another side-effect I have is slightly looser stools. But this isn't a big issue. I have been on it for 4 months, and will go to the doctor next month just to make sure all is well. But I would sure hate to give it up! I am not a big user of medication, and hope to be able to discontinue it at some point, which is apparently possible since I am menopausal and the headache thing seems to be hormone related. I think the main thing is to keep in touch with your physician, and try different things until you hit on the right one. Best Wishes.