Since my little sister was a baby, she has seemed to develop high fevers in the matter of minutes. When it first started, the doctors just thought she was dehydrated or allergic to milk. Now she is almost 5 years old and undergone many tests to determine what is wrong with her, as well as been put in the hospital about 15 times. She has had tests to determine what it is and they always come back as normal... from Pfapa to Luekemia... They thought she had Pfapa for about 2 years or more and now they aren't so sure. She can be playing outside and in the middle of nowhere, just lay down and almost fall asleep because her fever will be so high. Recently, the doctors removed her tonsils and they said that they were in the worst condition that they had ever seen. Recently, the doctors have started to think that she may have an immune deficiency because she can get sick very easily. Is there anyone out there with a child/ relative that can help out in this situation? Any information you can give as to what can be wrong with my little sister could help out greatfully. Thank you for your patience.

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No One

Hi No_one_350!
Welcome! http://www.healthboards.com/ubb/wave.gif

I cannot offer any suggestions as to what this very mysterious illness could be but I did want to welcome you here. There are some very intelligent folks on this board and I sure hope that they can offer some input.

Sorry about your little sister---God bless you all!

Thanks alot, hun. It means alot to me that someone could be so nice. There are hardly any people out there like that anymore. I hope I find something out about my little sister too. Thanks and bless you as well.

Lately there has been an enormous amount of information that is popping up about the necessity of maintaining high stores of Intracellular Glutathione (GSH). GSH is the body's Master Antioxidant. Without this important tri-peptide, the body will die. Low levels of GSH have attributed to many diseases including a range from Alzheimer's to Cancer to Immune Deficiency Syndromes.

There is only one company that I know of that can ascertain what the intracellular levels of Glutathione and other components within the mitochondria. I am unable to inform you as to the name of the company as it would constitute free advertising. Suffice it to say that the test is approximately $200 - $250.

There are a few ways of increasing the Intracellular levels of GSH. One way is to receive an IV of N-acetylcysteine (NAC). This is a common treatment at many hospitals that is usually used to assist the liver in detoxifying the body in extreme cases. The other every day and non-invasive method is to use a "functional food" that has been properly prepared so as to supply the necessary building bloskc that the body needs to build the Intracellular GSH.

Good luck with your little sister and God Bless you and your family in this difficult time.

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TNash
Director
Annasa
"Let thy food be thy medicine and thy medicine be thy food." - Hippocrates

I am wondering about dysautonomia. Autonomia is the bodies ability to control the autonomic nervous system. Body temperature control is just one of the many fuctions the ANS controls.

The bodies failure to properly maintain body temperature can be indicative of various disorders. It is generally considered a symptom rather than a disorder of and by itself.

The red flag for dysautonomia for me was when you mentioned her playing outside and spiking the temperature out of nowhere. By any chance was it exceptionally warm that day? 85+ degrees?

On warm days, a person with a typical ANS will sweat when they become warm. The blood pressure may lower as well as other autonomic functions that will make the body temperature not elevate.

With a person that has Dysautonomia, their body doesn't have the ability to maintain a normal temperature. They are in a way "cold blooded". The temperature rises, their body temperature rises. Some people, but not all, with body temperature regulation may also have a problem regulating cold.

Does she have any other issues? Regardless of how quirkly they may sound to you, they may be a clue.

For instance, does she complain about bright lights? The ANS is responsible to constrict the pupils when you go outside in bright light. Some people, not all, with Dysautonomia have a problem where their pupils don't constrict so bright lights bother them.

Does she have any issues with dizziness or light headedness when she stands? Again this is a function of the ANS.

Please keep in mind these are by no means the only functions controlled by the ANS. Just a small handfull of examples.

Bec

Have they check lueckocyte subsets? My daughter has had multiple doses of chemo and they look at her immune deficiencies thru the white blood cell subsets. they are checking to see if the cell that fight infection are low.
Might be something they can do?

Thanks everyone for all of the replies. My family and I were really needing them... we are trying to get everything taken care of. Hopefully we can soon. Thanks alot for all of your help. It means a great deal. Bless you all.

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--ME