momofsix
05-26-2005, 09:04 AM
I've started on hydromorphone-contin. It does seem to be helping quite a bit with the pain with very little in the way of side effects EXCEPT!!!! I am having severe and continuous jerking of my whole body most of the night so that I can't sleep (not during the day at all). I've read this is called myoclonus. Has anyone else experienced this? Does it pass as you get used to the medication, or is there something I can do about it? I hate to have to give up on this medication when it's seeming to really help.
Linda
Linda
Sponsor
feelbad
05-26-2005, 09:39 AM
Hi Linda,i am just curious,have you started any other new meds besides the palladone recently?(like within the last month or so?)i am just wondering as with narcotics, the type of side effect that you are describing really is rather unlikely but boy, after being on cymbalta for a little over a month,i had to do a rapid taper because of very extreme muscle spasms and horrid RLS type symptoms that just came out of nowhere one evening last week.I also developed some rather severe swelling in my joints and worsening of my RSD and central pain symptoms.any antisiezure type med or certain anti depressants would have the type of side effect that you described.But, when it comes to side effects or reactions to meds every person IS different.Just given the type of action that narcotics have on the body would really make it a highly unlikely response in most people.i hope you find the cuprit whatever it is.Marcia
momofsix
05-26-2005, 10:38 AM
No, this just started with the Palladone. I actually had noticed it with the regular hydromorphone as well so that I ended up switching my bedtime dose to percocet. I also take just 75 mg moclobomide in the mornings, so perhaps it's adding the Palladone that's the problem. I sure would like to be able to solve this one. My next step is Methadone, and I'd much rather stick with the Palladone.
Linda
Linda
feelbad
05-26-2005, 11:01 AM
I went to try and look up the drug you mentioned using both words but could not find any info using either spelling on any of the usual drug sites i normally use for info.Is this a really new med?You could be right about a possible med reaction between the two meds.i would ask your pharmacist about it.Marcia
Shoreline
05-26-2005, 12:35 PM
Hi Linda, Actually it's not that unusual. Any of the opiates can cause this. The normal meds used to treat them are the anti parkinsons meds, Miripex and Requip "US meds". I couldn't tolerate them but Klonopin seems to work better than anything else for me.
Marcia, Paladone is Purdues new US version of a 24 hour dilaudid formulation, HydromorphContin is Purdue Canada's 12 hour version of LA Dilaudid "hydromorphone"
I've actually seen folks have more problems with meth and morphine with these symptoms and haven't really noticed it with dilaudid in my pump. Maybe the Klonopin is just working well.
There are treatment options, Your other post mentioned Hydromorph Contin, so I assumed you are Canadian, as it's never been aproved for use in the states. Are you Canadain? Are you taking Palladone the 24 hour US med or HMC the 12 hour canadian med. Either way, Dilaudid is Diluadid "hydromorphone" It's no wonder you have the same effect from the LA med that you did with the SA med the only difference is the release mechanism between SA hydromorphone, HydromorphContin or Palladone.
You can find info at both Purdues sites, the US and Canadian.
Purdue canada
http://www.purdue.ca/products/products.asp
Purdue US
http://www.pharma.com/html/Our_products/Our_products.htm
The US site has the full prescribing info and all the effects on specific body funtions, Like cardio, nervous system, gastro, etc, The canadian site just has general consumer info so you might want to use the US site for info on Dilaudid in whatever form.
But it can be treated, I would try to mange the problem before switching away from a med that works to a med that's more notorius for causing this problem. Likely through trial and error and simple accomadation it will get better. At least i hope it does.
But your not an oddball and this isn't that unusual. It may be that I'm not having the problem because so little is actually used intrathecally, My pump is set at a hair over 3 mgs per day. When meds are deliverd IT, side effects are different, you still manufacturer endorphins and enkephlins unlike oral meds that can completely shut down production of endorphins and reduce dopamine which is usually the problem. The parkinsons meds work on dopamine production . Klonopin simply treats/prevents the symptom.
It's definitely too early to give up. I would talk to your doc after you have given it a week or two. You will sleep when your tired enough, but it does screw up sleep patterns when you nap in the day or late morning. :yawn: Hopefull they can find something to prevent or treat the RLS type symptoms or Myoclonus.
Take care, Dave
Marcia, Paladone is Purdues new US version of a 24 hour dilaudid formulation, HydromorphContin is Purdue Canada's 12 hour version of LA Dilaudid "hydromorphone"
I've actually seen folks have more problems with meth and morphine with these symptoms and haven't really noticed it with dilaudid in my pump. Maybe the Klonopin is just working well.
There are treatment options, Your other post mentioned Hydromorph Contin, so I assumed you are Canadian, as it's never been aproved for use in the states. Are you Canadain? Are you taking Palladone the 24 hour US med or HMC the 12 hour canadian med. Either way, Dilaudid is Diluadid "hydromorphone" It's no wonder you have the same effect from the LA med that you did with the SA med the only difference is the release mechanism between SA hydromorphone, HydromorphContin or Palladone.
You can find info at both Purdues sites, the US and Canadian.
Purdue canada
http://www.purdue.ca/products/products.asp
Purdue US
http://www.pharma.com/html/Our_products/Our_products.htm
The US site has the full prescribing info and all the effects on specific body funtions, Like cardio, nervous system, gastro, etc, The canadian site just has general consumer info so you might want to use the US site for info on Dilaudid in whatever form.
But it can be treated, I would try to mange the problem before switching away from a med that works to a med that's more notorius for causing this problem. Likely through trial and error and simple accomadation it will get better. At least i hope it does.
But your not an oddball and this isn't that unusual. It may be that I'm not having the problem because so little is actually used intrathecally, My pump is set at a hair over 3 mgs per day. When meds are deliverd IT, side effects are different, you still manufacturer endorphins and enkephlins unlike oral meds that can completely shut down production of endorphins and reduce dopamine which is usually the problem. The parkinsons meds work on dopamine production . Klonopin simply treats/prevents the symptom.
It's definitely too early to give up. I would talk to your doc after you have given it a week or two. You will sleep when your tired enough, but it does screw up sleep patterns when you nap in the day or late morning. :yawn: Hopefull they can find something to prevent or treat the RLS type symptoms or Myoclonus.
Take care, Dave
Director
05-26-2005, 01:33 PM
Hi Linda,
You're not odd at all, because there's a lot of people who experience this on opiates. My doctor called it Restless Leg Syndrome; although similair, it's not really RLS. I have it and have had it ever since going on Methadone. I'm at 180 mg, but I'm not sure dose has anything to do with it. I was on Oxycontin, 160 mg TID and Duragesic patch, 100 mg every 48 hours. Meth is the only med that I have taken that does this. So, I think it has to be the med.
I tried Mirapex and my wife said that the jerking (I have whole body jerks too) was actually worse, so I DCed. I am on 2 mg of Klonopin at bedtime and it's improved some, but not gone away. I'm really reluctant to up the Klonopin any more.
I would do what Dave suggested and that's give it some time. After a couple weeks, if it's still a problem then discuss it with your doctor. Good luck and please keep us posted. I am especially eager to follow you and to see how you do.
You're not odd at all, because there's a lot of people who experience this on opiates. My doctor called it Restless Leg Syndrome; although similair, it's not really RLS. I have it and have had it ever since going on Methadone. I'm at 180 mg, but I'm not sure dose has anything to do with it. I was on Oxycontin, 160 mg TID and Duragesic patch, 100 mg every 48 hours. Meth is the only med that I have taken that does this. So, I think it has to be the med.
I tried Mirapex and my wife said that the jerking (I have whole body jerks too) was actually worse, so I DCed. I am on 2 mg of Klonopin at bedtime and it's improved some, but not gone away. I'm really reluctant to up the Klonopin any more.
I would do what Dave suggested and that's give it some time. After a couple weeks, if it's still a problem then discuss it with your doctor. Good luck and please keep us posted. I am especially eager to follow you and to see how you do.
feelbad
05-27-2005, 09:56 AM
Hi Dave, i wasn't referring to the palladone,I know what that is,i was referring to the antidepressant that Linda is currently on,the Manerix?Or Moclobomide?i couldn't find a thing on any site I looked at that is why I asked if this was a very new med.Thanks,marcia
BrittleBones
05-27-2005, 10:05 AM
Hello Linda :wave: I have had similar side effects with Ultram and with other meds. I would describe my reaction as twitching and involuntary movements or jerks of my arms and legs. It doesn't happen continuously, and I've been able to ignore it. Now that I'm on Methadone, I don't notice it nearly as much. Kathy Mac
feelbad
05-27-2005, 10:11 AM
i also just wanted to mention that when I had asked my doc about my horrid leg spasms and if any of my meds could also be contributing to my spastcity I was told that it could not possibly be the OC i was on as narcotics don't usually bring out that kind of a reaction.what an idiot.i think that in my case, most is due to my damaged cortico spinal tract,among other things,but now I am thinking wayyy differently about my narcotics as being part of the problem as well.Hey Dave, would you consider being a pain doc?I would be the very first one sitting in your waiting room,lol.God I love this board!I find out soooo much more about pain control and problems here than I ever did from any of my docs.thanks for clearing that up for me.i really didn't know that.Sorry for posting wrong info to you Linda.Marcia