makingitright
05-27-2005, 11:29 AM
Does anyone know of a cholesterol med that does NOT effect the liver? My husbands liver enzyemes are slightly high so the dr. put him on Zetia, but all the info I've dug up on it still says that it can have a negative effect on the liver like the other drugs his dr. avoided because of his elevated liver numbers. alt 105, ast 52. Hep tests came back negative, so they are not sure why his liver is "upset". Are there any meds that have a less effect on the liver that we could check into?
Thanks to anyone who can help!
Thanks to anyone who can help!
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cathyinto
05-27-2005, 12:50 PM
Does anyone know of a cholesterol med that does NOT effect the liver? My husbands liver enzyemes are slightly high so the dr. put him on Zetia, but all the info I've dug up on it still says that it can have a negative effect on the liver like the other drugs his dr. avoided because of his elevated liver numbers. alt 105, ast 52. Hep tests came back negative, so they are not sure why his liver is "upset". Are there any meds that have a less effect on the liver that we could check into?
Thanks to anyone who can help!
How high are the cholesterol numbers? Have you worked on the diet to lower the cholesterol. I significantly lowered my cholesterol by eliminating "senseless" carbs, mostly by choosing low glycemic load foods. There have been several (hundreds?) good posts by people suggesting diets to try before jumping to medication.
Thanks to anyone who can help!
How high are the cholesterol numbers? Have you worked on the diet to lower the cholesterol. I significantly lowered my cholesterol by eliminating "senseless" carbs, mostly by choosing low glycemic load foods. There have been several (hundreds?) good posts by people suggesting diets to try before jumping to medication.
makingitright
05-27-2005, 03:07 PM
Thanks for the response. Yes, he's working on his diet. He's lost about 6 lbs with about 25 more to go!
His numbers are 284 total
Triglycerides 151
HDL 64
LDL 190
I know that the triglycerides is OK and the HDL is great but the LDL is so high, that's why the doctor advised the Zetia. He's been dieting for two weeks now, plus he's working out, and has not yet started the Zetia, because of the liver worries.
thanks again
His numbers are 284 total
Triglycerides 151
HDL 64
LDL 190
I know that the triglycerides is OK and the HDL is great but the LDL is so high, that's why the doctor advised the Zetia. He's been dieting for two weeks now, plus he's working out, and has not yet started the Zetia, because of the liver worries.
thanks again
makingitright
05-31-2005, 05:31 PM
anyone else know any drug that would not harm the liver as a possible side effect? I'm not sure if I mentioned it already or not but we are working on his diet like crazy and he is losing. However, even with his HDL being a great number we have to do something. His father had his first heart attack at 47. My husband is 40, so we'd like to take care of this as quickly as possible.
Thanks!!
Thanks!!
Uff-Da!
05-31-2005, 06:31 PM
Maybe someone else does, but I know of no drug to help cholesterol that is recommended for someone with liver problems. What exactly are you doing with regard to diet to lower cholesterol? Perhaps some of us could add some additional changes which could be helpful.
One supplement which you might want to research is Pantethine, which seems to have shown some success in improving the lipid profile. Plant sterols and psyllium (like Metamucil) might also be useful. Research studies have been done on all of these. I can't link them here, but you should be able to find them with a little looking.
One supplement which you might want to research is Pantethine, which seems to have shown some success in improving the lipid profile. Plant sterols and psyllium (like Metamucil) might also be useful. Research studies have been done on all of these. I can't link them here, but you should be able to find them with a little looking.
Lenin
05-31-2005, 06:42 PM
makingitright,
I think he can take the Bile acid resins like cholestyramine or cholestipol which never really enters the body proper but passes through the digestive tract and drags bile with it. The bile is rich in cholesterol and it can't get reabsorbed so the liver must pull cholesterol from the blood to make new bile.
I don't think this will effect the liver enzymes...typical side effects include things like bloating, gas, diarrhea and the like.
Zetia works in a similar manner to the resins but unfortunately Zetia (ezetimibe) must be broken down by the liver. It really is amontg the WORST choices for people with any signs of liver damage and is almost sure to worsen your husband's liver enzymes.
I think he can take the Bile acid resins like cholestyramine or cholestipol which never really enters the body proper but passes through the digestive tract and drags bile with it. The bile is rich in cholesterol and it can't get reabsorbed so the liver must pull cholesterol from the blood to make new bile.
I don't think this will effect the liver enzymes...typical side effects include things like bloating, gas, diarrhea and the like.
Zetia works in a similar manner to the resins but unfortunately Zetia (ezetimibe) must be broken down by the liver. It really is amontg the WORST choices for people with any signs of liver damage and is almost sure to worsen your husband's liver enzymes.
makingitright
06-02-2005, 10:26 AM
thank you very much, we will talk to his dr. and look further into it.
Much appreciated!
Much appreciated!
mikael26288
06-02-2005, 05:44 PM
Has the Doctor ruled out Gilbert's Syndome as why his liver is "upset". My liver enzyemes are always slightly high and they found out I had Gilbert's Syndome. They give me labs often to check my enzyemes while on cholestrol meds.