I have been suffering from depression for over a year now. I am taking celexa, clonazepam, trazodone, amtryiphline, zopiclone. I feel tired all the time and usually just have enough energy to get through work. I'm so far behind in everything else that I don't even know where to start. My moods vary quite rapidly and I have seemed to pick up a small drinking problem. Basically my life feels like such a mess. I do go for therapy for an hour a week for the last 10 months. My therapist has helped me quite a bit but lately it just seems like I don't have the strength to go on anymore. Has anyone felt like this?

I am taking celexa, clonazepam, trazodone, amtryiphline, zopiclone. I feel tired all the time and usually just have enough energy to get through work. .... I have seemed to pick up a small drinking problem.

This is no surprise that you feel so tired with so many drugs. Drugs are real poisons to the liver and this explains your tiredness. If you stop all these drugs for a few weeks or months *and* if your liver is not too much injured you will recover your previous energy.

In addition your drinking problem is a consequence of your liver injury. Liver injury indirectly leads to brain membrane rigidity and taking alcohol temporarely increases their fluidity (which makes you feel better mentally for a few hours). Brain membrane rigidity causes a total inactivation of a type of neurotransmitter receptors called metabotropic. As a result at this point no antidepressant will work any more. The inactivation of metabotropic serotonin receptors explains why antidepressants can aggravate a depression and cause suicidal ideations.

Instead of liver-toxic antidepressants take magnesium. It will increase your brain serotonin level safely. But it won't make your serotonin receptors work better. The first step needed will be to stop all drugs. To repair your liver you may take l-arginine, l-lysine, l-glutamic acid with vitamin E succinate and phosphatidylcholine. This will safely increase your brain membrane fluidity and and totally relieve you from depression.

Hi Lost & Tired,
Tell your GP your current feelings - it might be that a review of medication is needed. Keep going to your therapist too, it sounds as if you are having some sucess there.
Best of Luck,

Myshy