evolution88
12-20-2005, 11:10 AM
For those interested in the MS treatment Tysabri, we all know it is on fast track approval with the FDA. What I've been seeing by following the producers stock is that Biogen Idec is hiring like mad.
Many of the job postings available specifically talk about "Your job will be to market and sell the MS treatment Tysabri."
Obviously BIIB thinks their MS drug is coming back, and probably soon!
Many of the job postings available specifically talk about "Your job will be to market and sell the MS treatment Tysabri."
Obviously BIIB thinks their MS drug is coming back, and probably soon!
Sponsor
baddoey
12-20-2005, 02:06 PM
Has anyone talked to their neuro about this? my neuro said that she if/when it does get approved that she doesn't think it is a good idea for me - she is still concerned about the PML - even as a stand-alone therapy. . anyone else had any feedback?
evolution88
12-20-2005, 06:03 PM
Met with my Neuro today, he is excited about the return of Tysabri. His only comments are that Tysabri will be a stand alone drug, and would not be prescribed until it appeared the standard CRAB drugs were not working for the individual patient.
ron
ron
Moon Rising
12-22-2005, 07:17 PM
My neuro won't put me on it either untill further testing is done. She said it could be 2- 5 years before she had enough proof that it was safe before she gave it to any of her patients.
Moon
Moon
Curly100
12-29-2005, 07:01 PM
I really think it will be appoved, I guess I will be a guinea pig...
KelliD
12-29-2005, 08:07 PM
My neuro said there is not enough long-term testing to back up Tysabri's safety and he does notrecommend its use to his patients. I don't like the idea of ANY of the CRAB meds, BUT....Avonex (the one I am on) at least has a track record and to my knowledge, no one has died from its use! I'll take a pass on Tysabri for now.
evolution88
12-31-2005, 01:06 AM
KelliD,
It's good that Avonex is working for you. There are many out there that the CRAB drugs simply do not protect.
Those are the people who will probably opt for Tysabri as soon as it's available.
I'm lucky that Avonex seems to mostly be working for me, and my job won't allow me to start Tysabri until it's been released for one year. With that said, I've done a lot of reading on this drug and the deaths which may or may not have been directly involved in Tysabri.
I've no fear of the drug, and will take it as soon as it's available to me. I won't bore everyone with the details, but I'll sum it up with this:
It's effectiveness is well proven and nothing compares, it's dangers are unproven, and unclear, it's post infusion side effects are none.
Do your research, don't jump into it, but don't be afraid to try Tysabri if nothing else is working.
It's good that Avonex is working for you. There are many out there that the CRAB drugs simply do not protect.
Those are the people who will probably opt for Tysabri as soon as it's available.
I'm lucky that Avonex seems to mostly be working for me, and my job won't allow me to start Tysabri until it's been released for one year. With that said, I've done a lot of reading on this drug and the deaths which may or may not have been directly involved in Tysabri.
I've no fear of the drug, and will take it as soon as it's available to me. I won't bore everyone with the details, but I'll sum it up with this:
It's effectiveness is well proven and nothing compares, it's dangers are unproven, and unclear, it's post infusion side effects are none.
Do your research, don't jump into it, but don't be afraid to try Tysabri if nothing else is working.
peter falanga
12-31-2005, 04:21 PM
How is Tysabri given? I've been diagnosed in '86 and have ssince been on the ABC's as well as Novantrone. I'm 44 and M and have gotten tired last year of needles. Am interested that when Ty comes back, FDA has until 3/31/06 to make a decision, of going on it. My understanding was that the 3 people that died were imunocomprimesed before they started on Ty. Your thoughts wilbe helpful. I have read nothing but good.
Pete
Pete
evolution88
12-31-2005, 07:55 PM
Tysabri is given once a month via an IV infusion. Obviously you need to go into a doctor's office to receive the infusion.
You are correct, the individuals who passed did have compromised immune systems. Each was on other drugs which reduced their bodies immune system. Tysabri, like copaxone, isn't an interferon; it doesn't reduce the immune system.
I was on T for two months, and thought it was great. I felt no side effects, and felt very energetic. One study showed Tysabri completely eliminating MS relapses (that's eliminating, not reducing) in 50% of the people taking it. You will hear me talking about T often, I'm excited about it's return; until then I'm doing OK with Avonex. (At least as of the moment I type this)
For more info I go to ( REMOVED) financial section and monitor BIIB and ELN. BIIB and ELN are the companies that produce Tysabri. The message boards have a lot of financial and other stuff which doesn't mean much to me. However, they also will sometimes have links to articles about Tysabri and other MS medications.
Good Luck to all and lets hope for a Happy and Healthy New Year!
You are correct, the individuals who passed did have compromised immune systems. Each was on other drugs which reduced their bodies immune system. Tysabri, like copaxone, isn't an interferon; it doesn't reduce the immune system.
I was on T for two months, and thought it was great. I felt no side effects, and felt very energetic. One study showed Tysabri completely eliminating MS relapses (that's eliminating, not reducing) in 50% of the people taking it. You will hear me talking about T often, I'm excited about it's return; until then I'm doing OK with Avonex. (At least as of the moment I type this)
For more info I go to ( REMOVED) financial section and monitor BIIB and ELN. BIIB and ELN are the companies that produce Tysabri. The message boards have a lot of financial and other stuff which doesn't mean much to me. However, they also will sometimes have links to articles about Tysabri and other MS medications.
Good Luck to all and lets hope for a Happy and Healthy New Year!
peter falanga
01-01-2006, 07:18 PM
As I said, I was diagnosedd in '86. I retired on disability on '00. I invest now to keep busy.
Elan(ELN) is one of my companies that I own and have read a lot about. Looking forward to those infusions.
On a seperate note: Geron(GERN) is FDA approved to start an IND(investigational new drug) with embrionic stem cells this year. IMO this is where cures are going to come from. The trial is for spinal cords. Neurons are already being made. Scary, the possibilities. Be well.
Pete
Elan(ELN) is one of my companies that I own and have read a lot about. Looking forward to those infusions.
On a seperate note: Geron(GERN) is FDA approved to start an IND(investigational new drug) with embrionic stem cells this year. IMO this is where cures are going to come from. The trial is for spinal cords. Neurons are already being made. Scary, the possibilities. Be well.
Pete
evolution88
01-01-2006, 10:05 PM
On a seperate note: Geron(GERN) is FDA approved to start an IND(investigational new drug) with embrionic stem cells this year. IMO this is where cures are going to come from.
Pete
Agreed!
Pete
Agreed!