ARIZONA73
02-24-2006, 08:58 PM
If anyone is wondering which kind of CoQ10 is best to take, this study out of India should help steer you in the right direction. Subjects given hydrosoluble coenzyme Q10 (Q-Gel) experienced a net reduction of 22.6% for Lp(a), significantly increased their HDL, and experienced a significant decrease in blood glucose levels.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10077397&dopt=Abstract
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10077397&dopt=Abstract
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Lenin
02-25-2006, 11:16 AM
Thanks Arizona, it would be nice to believe but such a small short study isn't much to go on (25 people on Co-Q10, 22 on placebo for 28 days.)
A special sign of possible weakness of the study was the 8.2% decrease in Lp(a) from using a placebo. :confused:
(And it's also bad science to use 22 people and report results to the second significant number...but I quibble.)
I'm a poster boy for high Lp(a) and Co-Q10 at either 100 or 50 mg/day does nothing for me.
A special sign of possible weakness of the study was the 8.2% decrease in Lp(a) from using a placebo. :confused:
(And it's also bad science to use 22 people and report results to the second significant number...but I quibble.)
I'm a poster boy for high Lp(a) and Co-Q10 at either 100 or 50 mg/day does nothing for me.
ARIZONA73
02-25-2006, 11:29 AM
Lenin,
You're right, it is a small study. But it's interesting nevertheless. I think the problem with CoQ10, aside from the cost, is that it really is not absorbed very well. In fact, I've heard that with most forms of CoQ10, you may only absorb about 10%. But with the hydrosoluble form, it is much better absorbed, and you may be absorbing at least 50%. At least, this is what I have heard. Unfortunately, I have never seen the Q-Gel in stores. So I just order it online.
You're right, it is a small study. But it's interesting nevertheless. I think the problem with CoQ10, aside from the cost, is that it really is not absorbed very well. In fact, I've heard that with most forms of CoQ10, you may only absorb about 10%. But with the hydrosoluble form, it is much better absorbed, and you may be absorbing at least 50%. At least, this is what I have heard. Unfortunately, I have never seen the Q-Gel in stores. So I just order it online.
janeslk
02-25-2006, 07:06 PM
If anyone is wondering which kind of CoQ10 is best to take, this study out of India should help steer you in the right direction. Subjects given hydrosoluble coenzyme Q10 (Q-Gel) experienced a net reduction of 22.6% for Lp(a), significantly increased their HDL, and experienced a significant decrease in blood glucose levels.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10077397&dopt=Abstract
I was glad you posted this because I started reading up on CoQ10. Is it true that it takes as long as a year to actually build up in your system if you are taking the Q-sorb type capsules? I was probably reading an ad for the Q-gel type, but it said it only takes a few weeks at a lower dosage to get the same effect as Q-sorb at higher dosages over several months. Anyway, I ordered some for my guinea pig, uh, I mean my husband. Jane
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10077397&dopt=Abstract
I was glad you posted this because I started reading up on CoQ10. Is it true that it takes as long as a year to actually build up in your system if you are taking the Q-sorb type capsules? I was probably reading an ad for the Q-gel type, but it said it only takes a few weeks at a lower dosage to get the same effect as Q-sorb at higher dosages over several months. Anyway, I ordered some for my guinea pig, uh, I mean my husband. Jane
NHone
02-25-2006, 07:30 PM
I was glad you posted this because I started reading up on CoQ10. Is it true that it takes as long as a year to actually build up in your system if you are taking the Q-sorb type capsules? I was probably reading an ad for the Q-gel type, but it said it only takes a few weeks at a lower dosage to get the same effect as Q-sorb at higher dosages over several months. Anyway, I ordered some for my guinea pig, uh, I mean my husband. Jane
LOL, thats funny....You made my day with the guinea pig statement... A gentleman, M.d., Phd. at cornell said you should be able to replenish you Coq10 quiet quickly, (couple weeks) he alos found that Lipitor can deplete your Coq10 in as little as 13 days. There is a part of the brain the cerebellum that is highly seseptable to CoQ10 depletion. The reason for this is the cerebellum does not contain the same percentages of Coq10 as other parts of the brain and body. Therefore depletions will affect it first. If you read one of my other post I mentioned the original Framingham study that listed one of the factors of heart disease as being married to a highly educated woman.... if i were that guinea pig I might watch out.. Again thanks for the laugh.
LOL, thats funny....You made my day with the guinea pig statement... A gentleman, M.d., Phd. at cornell said you should be able to replenish you Coq10 quiet quickly, (couple weeks) he alos found that Lipitor can deplete your Coq10 in as little as 13 days. There is a part of the brain the cerebellum that is highly seseptable to CoQ10 depletion. The reason for this is the cerebellum does not contain the same percentages of Coq10 as other parts of the brain and body. Therefore depletions will affect it first. If you read one of my other post I mentioned the original Framingham study that listed one of the factors of heart disease as being married to a highly educated woman.... if i were that guinea pig I might watch out.. Again thanks for the laugh.
JJ
02-25-2006, 07:59 PM
LOL, thats funny....You made my day with the guinea pig statement... A gentleman, M.d., Phd. at cornell said you should be able to replenish you Coq10 quiet quickly, (couple weeks) he alos found that Lipitor can deplete your Coq10 in as little as 13 days. There is a part of the brain the cerebellum that is highly seseptable to CoQ10 depletion. The reason for this is the cerebellum does not contain the same percentages of Coq10 as other parts of the brain and body. Therefore depletions will affect it first. If you read one of my other post I mentioned the original Framingham study that listed one of the factors of heart disease as being married to a highly educated woman.... if i were that guinea pig I might watch out.. Again thanks for the laugh.
finres...didn't U post that beta blockers also deplete your system of C0Q10? I forgot where the post is, but was wondering about it, as hubby has been on Atenolol for a few years. He was also on Statins for years but got off of them due to side effects, and I'm not that fond of him being on Atenolol, as he is also type 2 diabetic.
We have an appt. with his cardio man March 7th, and I am going to ask about them switching some of his meds, as he has been having some problems that I think a change in meds. might help. We got his bloodwork report today, and I am not happy with it at all, but will post about it later.
Thanx for you input...... :wave:
finres...didn't U post that beta blockers also deplete your system of C0Q10? I forgot where the post is, but was wondering about it, as hubby has been on Atenolol for a few years. He was also on Statins for years but got off of them due to side effects, and I'm not that fond of him being on Atenolol, as he is also type 2 diabetic.
We have an appt. with his cardio man March 7th, and I am going to ask about them switching some of his meds, as he has been having some problems that I think a change in meds. might help. We got his bloodwork report today, and I am not happy with it at all, but will post about it later.
Thanx for you input...... :wave:
janeslk
02-26-2006, 11:08 AM
Thanks, Finres. I knew there was a reason I didn't pursue that doctorate degree. Jane
ARIZONA73
02-26-2006, 11:34 AM
I was glad you posted this because I started reading up on CoQ10. Is it true that it takes as long as a year to actually build up in your system if you are taking the Q-sorb type capsules? I was probably reading an ad for the Q-gel type, but it said it only takes a few weeks at a lower dosage to get the same effect as Q-sorb at higher dosages over several months. Anyway, I ordered some for my guinea pig, uh, I mean my husband. Jane
People, especially those who are taking statins, can easily ask their doctor to conduct a blood test that measures CoQ10. This would eliminate a lot of the guesswork as far as dosages are concerned, and the patient can adjust his dosage accordingly until adequate blood levels are achieved. I have read that a normal blood level is 0.8 to 1.2 micrograms per milliliter of blood. However, to obtain therapeutic benefits, experts say the level must be driven up into the 2.5 to 3.5 range through sustained supplementation. But everybody is different. What may be a good dosage for one person may not be adequate for someone else. For that reason, people should ask that this test be conducted. Doctors determine what dosage of statins to prescribe based on blood tests. So why should it be any different for CoQ10? I think that doctors are doing their patients a grave disservice by administering statins while ignoring CoQ10 blood levels. The two should go hand in hand.
People, especially those who are taking statins, can easily ask their doctor to conduct a blood test that measures CoQ10. This would eliminate a lot of the guesswork as far as dosages are concerned, and the patient can adjust his dosage accordingly until adequate blood levels are achieved. I have read that a normal blood level is 0.8 to 1.2 micrograms per milliliter of blood. However, to obtain therapeutic benefits, experts say the level must be driven up into the 2.5 to 3.5 range through sustained supplementation. But everybody is different. What may be a good dosage for one person may not be adequate for someone else. For that reason, people should ask that this test be conducted. Doctors determine what dosage of statins to prescribe based on blood tests. So why should it be any different for CoQ10? I think that doctors are doing their patients a grave disservice by administering statins while ignoring CoQ10 blood levels. The two should go hand in hand.