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cartner
03-22-2006, 04:46 AM
Hi,

Someone told me that there are 2 new drug classes that will be in the market by 2007 or 2008. Does anyone heard about that?
Thanks,
Michael

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Lenin
03-22-2006, 08:15 AM
Nothing new on the horizon that I've heard of. A couple for pulmonary hypertension (a different animal) and a couple new uses for old drugs (sildenafil <Viagra>for pulmonary hypertension.>
Doctor says " Are you just happy to see me or is that your hypertensive medication talking!" :D:D

Oh yeah, Astra Zeneca is pushing ATACAND <candesartan> as a treatment for those who are PRE-HYPERTENSIVE...to delay the disease.
I wonder if they will start selling pills to treat all of us who haven't yet developed cancer, Alzheimer's, and meningitis? :D:D:D

Nothing new.

cartner
03-22-2006, 08:41 AM
Hello Lenin,

I have read about a new drug class called renin inhibitors? and another drug class but I don't remember its name. Do you know what it's?
Thanks,
Michael

Lenin
03-22-2006, 09:04 AM
The entry in the renin inhibitor class is called Aliskiren. Personally I think the drug is attacking the process of Angiotensin production too far upstream. I can almost SMELL the possibility of numerous unimagined side effects...like strangling a person to cure his hyperventilation :D:D!
We shall know more when they present their studies.

One thing for sure, if Speedel comes out with the Aliskiren, the publicity mills will begin churning ENDLESS studies showing how dreadfully useless ACE inhibitors and ARB's have been all these years...I wonder if we can claim a refund for the wasted money! :D:D:D

Thanks for calling my attention to it...I'd not read anything before about it.

cartner
03-22-2006, 09:29 AM
Lenin,

So you think it will have more side effects than the current classes? I have read that the side effects will be less than ACEs and ARBs but how can we be sure :(?

By the way, have you read about the other new drug class?
Thanks,
Michael

pal7778
03-22-2006, 02:32 PM
Is the renin inhibitor supposed to be much more effective?

Lenin
03-22-2006, 08:55 PM
The claim is that current methods allow renin to be made into angiotensin-2 by other methods if the main routes are subverted as in ACE inhibition or incompletely blocked as in ARB blocking.
There is always angiotensin-2 sneaking in, the hope of the new drug is to prevent it by blocking renin production. Risky business because without blood pressure, we are flat-lined corpses.

lane413
03-23-2006, 06:33 PM
Lenin, you've made my evening. So you think the new class will "strangle us into lower bp?" You are so funny! I think I'll use that when I go with my mom to her next dr. appt. the dr. is always adding new "pills" to lower her bp even when it's 130/70.





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