I had been taking Aloe Vera capsules for constipation (and anal fissure) for a few days, but that produced loose stool so I stopped. I bought some Metamucil but I haven't taken it yet because I don't know if I'm supposed to take anything else with it, like the Aloe Vera in order for it to not irritate the fissure. Thanks!

Metamucil is a water soluble fiber supplement and is designed to be taken on its own, but mixed with water though. Ensure you do drink plenty of water with it to flush it through your system and try to increase your water intake generally. You may notice that you get a bit of a bloated belly when you first start taking it. This will pass when your system gets used to it. You need to keep taking for at least 2 weeks to really decide if it is working for you or not and if it is then carry on taking it.