PaulaMc
07-23-2006, 01:33 PM
Hello
I'm new to this site. I have had chronic pain for 12 years. I have degerative bone disease in my neck, Fybromyalgia and osteoarthritis. For the past 3 1/2 I have been taking oxycodone 5 mg 2 tabs 4 times daily. Last fall my pain began to get increasingly worst. My doctor had been treating flare ups by increasing the oxycodone to 3 tabs 4 times daily. Over the last 4 to 5 months the medication was not working as well. The pain medication was not lasting until it was time to take the next dosage and was not helping the pain as it had in the past. I have tried Azenza, Methadone all with really awful side effects. Last week my doctor switched me to oxycodone hcl ER 40 mg 2x daily. Is this a dosage thats equal to or more potent than the short acting oxycodone I was taking? It seems to work better but doesn't always control the pain for 12 hours. Has anyone had this problem? Other than that I don't seem to be having any negative side effects.
Thanks for your help
I'm new to this site. I have had chronic pain for 12 years. I have degerative bone disease in my neck, Fybromyalgia and osteoarthritis. For the past 3 1/2 I have been taking oxycodone 5 mg 2 tabs 4 times daily. Last fall my pain began to get increasingly worst. My doctor had been treating flare ups by increasing the oxycodone to 3 tabs 4 times daily. Over the last 4 to 5 months the medication was not working as well. The pain medication was not lasting until it was time to take the next dosage and was not helping the pain as it had in the past. I have tried Azenza, Methadone all with really awful side effects. Last week my doctor switched me to oxycodone hcl ER 40 mg 2x daily. Is this a dosage thats equal to or more potent than the short acting oxycodone I was taking? It seems to work better but doesn't always control the pain for 12 hours. Has anyone had this problem? Other than that I don't seem to be having any negative side effects.
Thanks for your help
Sponsor
Queenneeee
07-24-2006, 04:17 AM
HI PaulaMc welcome !! I am new too,just found these boards last week and I am already so hooked and happy to finally find a place where we all can relate. Sorry to hear about your pain and I really have no answers for you but I do have a question for you .. I was to start avenza last week but I am nervous to try it can u enlighten me with your experience on avenza you said you had side effects from it ..thanks in advance and WELCOME again ,
Shoreline
07-24-2006, 09:16 AM
Hi Paula, Long acting Oy or OyyContin and the generics use a dual phasic release, meaning half it's mg strength is released during the firstyt hour and the other half at around the 6th. So a 40 mg oxy sustains roughly 20 mgs in your system for it's duration. For most it's closer to 8 hours than 12. So that would be roughly the ame as taking 4 5mg oxycodone tablets every 6 hours. Thwe problem is that oxy doesn't last 6 hours whether it's an instant release version or what is released from the LA version. The advantage is to sustain the level of medication so that you treating the pain before it gets totaly out of control. The disadvantage is that you become dependnet on the med much quicker than you would taking it as needed where some days you dose would be minimal and during flairs you have been taking a higgher dose. Your body gets used to the drug so when you do have a flair you will likely need some method to ddeal with additional pain. Some docs use short acting meds for break through pain and other docs want you to use methods you learn during your years of trial and error with other methodds. relaxation techniques, stretching, heat, ice, gtopical creams and lidoderm patches. Every doc is different and if this is your GP treating your pain he isn't going to have the tools to manage chronic pain other than a script pad. I consider being dependnet on meds a large price to pay and a last resort. If your 40 now, you have another 30 years of chronic pain to live with. IF your only method of pain management is narcotics, your dose will slowly rise and become less effective over the years if you don't take advantage of the relief your getting now and do the stretches and excercises to keep the fibro under control.
You might want to consider seing a PM doc since your pain is severe enough to need meds once reseerved for cancer pain. PM docs should be better triained and have more to offer than just a script pad. People with cancer don't have their pain treated by their GP, it's a specialty so when GP's cross the line and start playing specilaist, your really not geting the care you deserve or that may benefit you more than the simple answer which is take more pain meds which a GP can supply but knows little about. The simple answer has a pretty hefty price to pay for relief and at some point your dose will reach levels your GP just isn't aware of. In the old days before OxyContin "1996" if you had spine surgery, joints replaced, kidneys remobved, the strongest med you would have been given was 5 mg percocet.
Oxy is notorious for developing rapid tolerance and only lasting 8 hours. If your prescribing doc isn't a PM doc, he isn't going to know what to do with you in 10 years. The prescribing information and the anufacturer stuill insist OxyContin, The name brand version lasts 12 hours. If your GP knows nothing more about the med than what he read in the prescribing info, that's likely what your going to get.
Good luck and you should really llok for a PM doc or clinic that can do more than write script. for pain killers. The goal of PM isn't to eliminate all your pain, it's to manage your pain enough to make it tolerable so you can do the things you need to do to prevent further muscle wasting and stiffnees and improve your ability to function.
IF the meds impair you more than your DX's than you really need a specialist that knows what he's doing. It blows me away to hear about a GP prescribing methadone to a CP patient. It's considered a 3rd or 4th tier drug that you use as a last resort. IF your GP Diagnosed you, I wouldn't even be convinced the GP was right. Have you had a surgical consult to really look into the neck problems, they can mimik most of the symptoms of fibro. If there is a surgical solution, or interventional procedure like trigger point injections, epidural steroids, nerve blocks,,even Botox is being used more and more to treat neck muscles that are constantly in spasm. Robaxin infusion can be helpful, tens units, even acupunctuiure, chiro , and myofacial release techniques are all things PM doc specialize in and are trained to do that your GP isn't.
These are so many things a GP just can't offer,you should really look for proper pain management that takes a multi faceted aproach. A good doc isn't one thsat just gives you what you want or more of the same that used to work. If you can find other modalities to manage your pain or at least decrease your need for pain meds It's better than spending the next 30 years dependent on pain meds and slowly increasing your dose to keep up with developing tolerance if you have other options you haven't tried.
Good luck and welome, Dave
You might want to consider seing a PM doc since your pain is severe enough to need meds once reseerved for cancer pain. PM docs should be better triained and have more to offer than just a script pad. People with cancer don't have their pain treated by their GP, it's a specialty so when GP's cross the line and start playing specilaist, your really not geting the care you deserve or that may benefit you more than the simple answer which is take more pain meds which a GP can supply but knows little about. The simple answer has a pretty hefty price to pay for relief and at some point your dose will reach levels your GP just isn't aware of. In the old days before OxyContin "1996" if you had spine surgery, joints replaced, kidneys remobved, the strongest med you would have been given was 5 mg percocet.
Oxy is notorious for developing rapid tolerance and only lasting 8 hours. If your prescribing doc isn't a PM doc, he isn't going to know what to do with you in 10 years. The prescribing information and the anufacturer stuill insist OxyContin, The name brand version lasts 12 hours. If your GP knows nothing more about the med than what he read in the prescribing info, that's likely what your going to get.
Good luck and you should really llok for a PM doc or clinic that can do more than write script. for pain killers. The goal of PM isn't to eliminate all your pain, it's to manage your pain enough to make it tolerable so you can do the things you need to do to prevent further muscle wasting and stiffnees and improve your ability to function.
IF the meds impair you more than your DX's than you really need a specialist that knows what he's doing. It blows me away to hear about a GP prescribing methadone to a CP patient. It's considered a 3rd or 4th tier drug that you use as a last resort. IF your GP Diagnosed you, I wouldn't even be convinced the GP was right. Have you had a surgical consult to really look into the neck problems, they can mimik most of the symptoms of fibro. If there is a surgical solution, or interventional procedure like trigger point injections, epidural steroids, nerve blocks,,even Botox is being used more and more to treat neck muscles that are constantly in spasm. Robaxin infusion can be helpful, tens units, even acupunctuiure, chiro , and myofacial release techniques are all things PM doc specialize in and are trained to do that your GP isn't.
These are so many things a GP just can't offer,you should really look for proper pain management that takes a multi faceted aproach. A good doc isn't one thsat just gives you what you want or more of the same that used to work. If you can find other modalities to manage your pain or at least decrease your need for pain meds It's better than spending the next 30 years dependent on pain meds and slowly increasing your dose to keep up with developing tolerance if you have other options you haven't tried.
Good luck and welome, Dave
PaulaMc
07-25-2006, 05:46 PM
Hi Dave
I guess I didnt give you enough info in the first post. I have had Physical Therapy on 5 different occations. I have seen a neurologist and an neurosurgeron, I do have 3 bulging disks in my neck, and degerenative disk disease, but at this point no one thinks surgery is my best option. I have had Epidural injections in my spine and at a pain clinic. They didn't help. I was diagnosed by an arthritis specialist for the fibro and osteoarthritis. I have a muscle stimulator that I use 2x a day. I also do streches 4 times a day and walk for 1/2 to 1 hour depending on pain level. MY GP is also a DO he does chiro work on me and trigger point injections. I have tried many pain releivers other than narcotics but the pain has gotten out of control over the past year. My doctor is very careful prescribing narcotics, however he does not feel comfortable allowing me to manage them myself. Which doesnt always work. I have asked him to prescribe my monthly amount and enough to get me through a flair, especially if the flair happens on a weekend or when he's on vacation. He refuses. So I am left to suffer until I can get in touch with him. I was wondering about the new medication because sometimes during the day it seems to be working really well and at other times it doesn't. I under stand that I'm never going to be pain free but I would at least like to be able to get out of bed, and there are days on end when I can't. Thanks for your responce I really appreciate your help
Paula
I guess I didnt give you enough info in the first post. I have had Physical Therapy on 5 different occations. I have seen a neurologist and an neurosurgeron, I do have 3 bulging disks in my neck, and degerenative disk disease, but at this point no one thinks surgery is my best option. I have had Epidural injections in my spine and at a pain clinic. They didn't help. I was diagnosed by an arthritis specialist for the fibro and osteoarthritis. I have a muscle stimulator that I use 2x a day. I also do streches 4 times a day and walk for 1/2 to 1 hour depending on pain level. MY GP is also a DO he does chiro work on me and trigger point injections. I have tried many pain releivers other than narcotics but the pain has gotten out of control over the past year. My doctor is very careful prescribing narcotics, however he does not feel comfortable allowing me to manage them myself. Which doesnt always work. I have asked him to prescribe my monthly amount and enough to get me through a flair, especially if the flair happens on a weekend or when he's on vacation. He refuses. So I am left to suffer until I can get in touch with him. I was wondering about the new medication because sometimes during the day it seems to be working really well and at other times it doesn't. I under stand that I'm never going to be pain free but I would at least like to be able to get out of bed, and there are days on end when I can't. Thanks for your responce I really appreciate your help
Paula
PaulaMc
07-25-2006, 05:50 PM
Hi
I took avenza for about 2 months. I didnt find it worked as well as the oxycodone. The side effects I had were, severe night sweats, constant itching, Insomnia, and when I did sleep I had very bad nighmares. Thanks for answering my post. Hope I was some help to you.
Paula
I took avenza for about 2 months. I didnt find it worked as well as the oxycodone. The side effects I had were, severe night sweats, constant itching, Insomnia, and when I did sleep I had very bad nighmares. Thanks for answering my post. Hope I was some help to you.
Paula
Director
07-25-2006, 06:38 PM
Hi Paula: I was going to respond and tell you about how Oxycontin (Oxycodone ER) works and releases the medication, but Dave had already done his usual excellent job of explaining it to you. Like Dave said, the medication you're on rarely lasts for the full 12 hours they say it will. When I was on Oxycontin (and most others too) I had three times a day dosing from day one. My doctor wasn't even going to try the 12 hour dosing. I also had Roxicodone, 30 mg for breakthrough pain. I'm sorry, I don't recall, but are you on anything for BT pain?
I'm also very curious what kind of negative side effects you got from Methadone when you were on it? How long were you on it and at what dose? I'm on Meth myself currently, and I take 180 mg per day. It has always worked great for me and with only minimal side effects. It is especially good on nerve pain. How did the Meth compare to the Avenza for you?
I'm glad to hear for the most part, you are getting positive effects. Do you know if your doctor would be receptive to increasing your dose of the Oxy to three times a day? What Dave said, was exactly what happened to me. I was at 160 mg TID at the end, but the tolerance to the med went up quite quickly. If you can get on three times a day dosing and/or get breakthrough meds, that will help you quite a bit.
Good luck to you and let us know how you do with the medication, especially the doseage.
I'm also very curious what kind of negative side effects you got from Methadone when you were on it? How long were you on it and at what dose? I'm on Meth myself currently, and I take 180 mg per day. It has always worked great for me and with only minimal side effects. It is especially good on nerve pain. How did the Meth compare to the Avenza for you?
I'm glad to hear for the most part, you are getting positive effects. Do you know if your doctor would be receptive to increasing your dose of the Oxy to three times a day? What Dave said, was exactly what happened to me. I was at 160 mg TID at the end, but the tolerance to the med went up quite quickly. If you can get on three times a day dosing and/or get breakthrough meds, that will help you quite a bit.
Good luck to you and let us know how you do with the medication, especially the doseage.
PaulaMc
07-26-2006, 04:49 PM
Hi
Thank you all for your responses they have helped very much. I have been on Methadone 2 times. My begining dosage was 20mg 3 times a day. At first I was just really out of it, but figured my body would adjust to the new medication. On day 3 I began to get a headache and it seemed to get worst with every dose I took. By the 6th day I was still really out of it (couldn't drive, very unstable on my feet and kept falling asleep). I also was having difficulty sleeping and when I did had nightmares. On the 7th day I returned to the doctor and he discontinued the Methadone. The 2nd time I tried to take it, I started out at 5mg 3x daily and slowly increased. I got to 10mg 3 times daily and the headaches began again also other symptoms described above with little pain relief. Oh and I also had no appetite at all, not really nausated just didn't feel like eating. The Azenza was basicly the same with out the headache, and severe itching that almost drove me crazy. Right now I have oxcodone 5mg 1 to 2 tabs for break through pain, but the doc says he wants me off the short acting all together, So I expect he will be increasing the oxy Er at my next appointment. because I am still having to use the oxy 5 mgs. on average 2 to 3 times a day. I'm not sure about the Oxy 3 times a day. I think he's trying to see how small a dose I can take and still get adequate pain relief. I was taking Tramadol 100mg PRN for Bt pain but I started a new antidepressant and it was interacting with it. Thats what basicly started this medication change.
Paula
Thank you all for your responses they have helped very much. I have been on Methadone 2 times. My begining dosage was 20mg 3 times a day. At first I was just really out of it, but figured my body would adjust to the new medication. On day 3 I began to get a headache and it seemed to get worst with every dose I took. By the 6th day I was still really out of it (couldn't drive, very unstable on my feet and kept falling asleep). I also was having difficulty sleeping and when I did had nightmares. On the 7th day I returned to the doctor and he discontinued the Methadone. The 2nd time I tried to take it, I started out at 5mg 3x daily and slowly increased. I got to 10mg 3 times daily and the headaches began again also other symptoms described above with little pain relief. Oh and I also had no appetite at all, not really nausated just didn't feel like eating. The Azenza was basicly the same with out the headache, and severe itching that almost drove me crazy. Right now I have oxcodone 5mg 1 to 2 tabs for break through pain, but the doc says he wants me off the short acting all together, So I expect he will be increasing the oxy Er at my next appointment. because I am still having to use the oxy 5 mgs. on average 2 to 3 times a day. I'm not sure about the Oxy 3 times a day. I think he's trying to see how small a dose I can take and still get adequate pain relief. I was taking Tramadol 100mg PRN for Bt pain but I started a new antidepressant and it was interacting with it. Thats what basicly started this medication change.
Paula
bjeanne
07-26-2006, 11:12 PM
Wow! Hi Paula:
I'm new-ish, also. I can't believe that our stories regarding methadone sound so similar. I was terrified to take this med., but nothing else was helping and for whatever reason, my PM doc doesn't seem to be very fond of long acting opiates. He never tried them on me.
The methadone was so terrible for me and I didn't know what the nightmares and night sweats were from. The answer I got from the clinic nurses, regarding sweats: MENOPAUSE. I'm 43 years old. I've been with them for almost 7 months and never had these symptoms before methadone and this is the response I have gotten. I am relieved to see someone else (sorry for both of us, but relieved not to be alone) have similar side effects. I've stopped this medication and am not doing well.
I wish you the best of luck
Barb
I'm new-ish, also. I can't believe that our stories regarding methadone sound so similar. I was terrified to take this med., but nothing else was helping and for whatever reason, my PM doc doesn't seem to be very fond of long acting opiates. He never tried them on me.
The methadone was so terrible for me and I didn't know what the nightmares and night sweats were from. The answer I got from the clinic nurses, regarding sweats: MENOPAUSE. I'm 43 years old. I've been with them for almost 7 months and never had these symptoms before methadone and this is the response I have gotten. I am relieved to see someone else (sorry for both of us, but relieved not to be alone) have similar side effects. I've stopped this medication and am not doing well.
I wish you the best of luck
Barb

