It all started after brain surgery. I feel like my bones want to jump out of my skin. It is the most irritating feeling. It started off slowly and now is horrible. The doctor put me on 50 mg.zoloft(cant take anymore because of seizure meds.)which helps sometimes but not all the time. Its been getting so bad that I cant sleep at night. (seems to be really bad first thing in the morning and before I go to sleep. Does anyone else know what this is.Is this even anxiety? Any advise would be nice. Thanks

I would check with your doctor, because you have had brain surgery. But ask them about Topomax i believe it is for seizures but also depression and anxiety. Sounds like maybe you are experiencing depersonalization, i have been getting that lately with all of the anxiety i have been having i want to crawl right out of my skin. it is a twisted feeling.