Hi everyone. I am lurking on this board, trying to find out what's wrong with my sister. She is having the numbness, heavy legs and arms and having trouble walking. It came on quite suddenly - so much so, that she went to the ER thinking she might be having a stroke or heart attack!! Well, they ruled all of that out. So far, she's had MRI, MRA, EKG, CAT Scan, sono of carotid artery, MRI of lumbar & thoracic, stress test (medically induced because she couldn't walk fast enough to get her heart rate up) and she's seen an opthamologist because this all started with her vision going blurry while driving one day. She had a retinal hemorrage in her eye. Sooooo - after all that - and all the tests coming back negative, they have told her to just sit tight and come back in 2 weeks and see if it's gotten any better? She has been to a neurologist too. She's beside herself....and she is now giving up driving, because she can't feel whether she's pushing down on the accellerator or not. She described her legs and arms as "walking through taffy". I guess the last thing to do would be to get the spinal tap done to get a definite diagnosis for MS? They were also thinking it might be a case of Guilliane's Barre? She is also waking up in the middle of the night with a racing pulse - and that happened in the ER too - fine one minute, then a racing pulse the next, then back to fine. Does this sound like MS?? Thanks for all your posts - they really do help everyone....it's scary how many people are out there walking around in pain, with something wrong, and none of the doctor's can figure it out!! All of her tests are showing up that she's a healthy 47 year old woman...