Does anyone know what this is in plain English? What does it mean when it is high?:confused:

TIBC =Total IRon Binding Capacity. The easiest definition I can give you is that this test tells the doctor how much iron is sticking to the blood cells to try to make them transport oxygen. It is a complex system. If the TIBC is high, it usually means something has gone wrong in the iron regulation system. It is something that has to be addressed by your hematologist.