I am currently taking low dose Naltrexone for my MS but I have read on the website that it helps with Fibromyalgia as well. I've been on it for about 16 months now and so far so good. I am so hoping that it will do what is meant to do and that is to halt progression of my disease. Perhaps it could help you all too. Perhaps it would help if I explained exactly how the low dose naltrexone works. Naltrexone taken in such a low almost homeopathic dose of 4.5mg, as opposed to the 50 mg FDA approved dose, causes the body to create a large amount of endorphins. Kind of like when you run or do aerobics. Anyway, Dr. Bihari in New York believes that all auto immune diseases are more the cause of low endorphins which compromises the immune system. The same with cancer and aids. Once you upregulate the endorphins back to normal, that in turn regulates the immune system back to normal. He has been working with this approach for many years with cancer and aids patients with great success. One can only hope that one day this therapy will get to the mainstream. I for one don't have time for a multi -million dollar clinical trial for this. Believe me it works. Just wish I was more familiar with how it might help with Fibromyalgia. Check out the website. Don't think I am allowed to post it here but if you type low dose naltrexone into a search engine it should come up. Dr. Bihari was just interviewed on a radio station in NY....wbai and I was able to obtain an audio tape of it...quite fascinating. Good luck to all and I sure hope that you all find what works for you...{{{hugs}}}

Thank you Joyce for posting here. I have been on for almost 6 months now, and it has made a huge difference in how I feel in general. No more morning pain and stiffness! This is the only drug I have tried in 20 years that brings such good relief. I am having a problem with some anxiety for the past 6 weeks, but that is not unusual with fibromyalgia.
My family has noticed that I am more even tempered, doing more chores and the best thing is that I am walking and even running about a block at a time during the walk! LDN, I believe, has prevented me from developing a permanent case of Reflex Sympathetic Dystropy from a foot/ankle injury. I was on month 2 of LDN when I injured it. I started to develop RSD. My leg swelled and became hot and very painful. I was checked for blood clots, which was negative. In month three it started to heal. By month four all signs of RMD went away and all pain was gone. Today there is no sign of a former injury.
I seldom get a flare. I do get some muscle spasms when I over-work my muscles but I do not need meds as often for that.
LDN has made my life more bearable. I was quite a mess and taking more and more drugs before I started low dose naltrexone. Actually, I thought I would be in a wheel chair by now due to the total body pain. I have had fibromyalgia and back, neck, and shoulder pain for over 20 years. More fibro sufferer's should explore this option! MistyMisty

Hey Misty...so glad to hear how well you are doing with the LDN. I just finished an audio tape of an interview that Dr. Bihari gave on wbai in New York a few weeks ago. I swear that I become more and more enlighted about it all and it truly is amazing. If only more people would become aware of it. I just feel so compelled to help spread the word. I know it sounds too good to be true and one big road block is that no pharmaceutical company is gonna wanna spend the millions it takes for clinical trials for it because there is no hope for a patent at this late date. People just need to do a little research about it and get assertive with their doctors. I did and am feeling really good about the fact that I took control of my life and found a doc willing to listen to what I wanted to do. No need to be afraid of this drug at such a low dose...there is absolutely no risk in taking it....nothing to lose right? I just hope that I can help spread the word in my own small way. Once again...good for you...{{{hugs}}} JoyceF